Primary malignant mesothelioma developed in liver

Dong-Sik Kim, Sung Gyu Lee, Sun Young Jun, Won Kim Kyoung, Tae Yong Ha, Keon Kuk Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The following reports a rare case of primary localized malignant mesothelioma of the liver. A 53-year-old man with no history of exposure to asbestos was admitted to our department for evaluation of incidentally detected liver mass. Computed tomography and hepatic angiogram showed a tumor at the dome of the liver, which was fed mainly through the inferior phrenic artery. The mass was resected, including a portion of the diaphragm. Microscopically, the tumor was composed of cord-like or trabecular arrangements of epithelioid cells having abundant eosinophilic cytoplasm and prominent nucleoli. Immunohistochemically, the tumor cells were strongly positive for calretinin and cytokeratin 5 and negative for hepatocyte markers. These findings were consistent with our diagnosis of epithelioid mesothelioma. A local recurrence was noted 15 months after surgery, which was treated by radiofrequency ablation. At 23 months after initial surgery, locally recurrent masses with direct invasion of the diaphragm and a solitary intrahepatic metastasis were noted, which was treated by partial excision of the diaphragm with intraoperative RFA after transarterial chemoembolization.

Original languageEnglish
Pages (from-to)1081-1084
Number of pages4
JournalHepato-Gastroenterology
Volume55
Issue number84
Publication statusPublished - 2008 May 1
Externally publishedYes

Fingerprint

Diaphragm
Liver
Pleural Solitary Fibrous Tumor
Keratin-5
Calbindin 2
Epithelioid Cells
Neoplasms
Asbestos
Mesothelioma
Hepatocytes
Angiography
Cytoplasm
Arteries
Tomography
Neoplasm Metastasis
Recurrence
Malignant Mesothelioma

Keywords

  • Hepatic tumor
  • Malignant mesothelioma
  • Mesothelioma

ASJC Scopus subject areas

  • Medicine(all)
  • Hepatology
  • Gastroenterology

Cite this

Kim, D-S., Lee, S. G., Jun, S. Y., Kyoung, W. K., Ha, T. Y., & Kim, K. K. (2008). Primary malignant mesothelioma developed in liver. Hepato-Gastroenterology, 55(84), 1081-1084.

Primary malignant mesothelioma developed in liver. / Kim, Dong-Sik; Lee, Sung Gyu; Jun, Sun Young; Kyoung, Won Kim; Ha, Tae Yong; Kim, Keon Kuk.

In: Hepato-Gastroenterology, Vol. 55, No. 84, 01.05.2008, p. 1081-1084.

Research output: Contribution to journalArticle

Kim, D-S, Lee, SG, Jun, SY, Kyoung, WK, Ha, TY & Kim, KK 2008, 'Primary malignant mesothelioma developed in liver', Hepato-Gastroenterology, vol. 55, no. 84, pp. 1081-1084.
Kim D-S, Lee SG, Jun SY, Kyoung WK, Ha TY, Kim KK. Primary malignant mesothelioma developed in liver. Hepato-Gastroenterology. 2008 May 1;55(84):1081-1084.
Kim, Dong-Sik ; Lee, Sung Gyu ; Jun, Sun Young ; Kyoung, Won Kim ; Ha, Tae Yong ; Kim, Keon Kuk. / Primary malignant mesothelioma developed in liver. In: Hepato-Gastroenterology. 2008 ; Vol. 55, No. 84. pp. 1081-1084.
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