Primary neuroendocrine carcinoma of the breast with clinical features of inflammatory breast carcinoma: A case report and literature review

Do Hyung Lee, Ah Young Park, Bo Kyoung Seo, Young Sik Kim, Ki Yeol Lee, Sang Hoon Cha

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Primary neuroendocrine carcinoma of the breast (NECB) is a very rare type of invasive breast carcinoma. Most NECBs appear on breast imaging as solid masses of varied shapes and margins, and have worse clinical outcomes than does invasive ductal carcinoma, not otherwise specified. However, there have been no reports to date regarding NECB with features of inflammatory breast carcinoma. Here, we describe the clinical, radiol-ogic, and pathologic findings of the first reported case of primary NECB presenting as inflammatory breast carcinoma. The patient complained of diffuse right breast enlargement and erythema. Mammography identified severe breast edema and axillary lymphadenopathy. Ultrasound detected an irregular, angular, hypoechoic mass with dermal lymphatic dilatation. On magnetic resonance imaging, the mass had rim enhancement and the entire right breast showed heterogeneous enhancement with malignant kinetic features. Pathology identified the mass as a primary NECB with positive for synaptophysin, CD56, estrogen and progesterone receptors.

Original languageEnglish
Pages (from-to)404-405
Number of pages2
JournalJournal of Breast Cancer
Volume18
Issue number4
DOIs
Publication statusPublished - 2015 Dec 1

Keywords

  • Breast neoplasms
  • Magnetic resonance imaging
  • Neuroendocrine carcinoma
  • Ultrasonography

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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