Abstract
Primary neuroendocrine carcinoma of the breast (NECB) is a very rare type of invasive breast carcinoma. Most NECBs appear on breast imaging as solid masses of varied shapes and margins, and have worse clinical outcomes than does invasive ductal carcinoma, not otherwise specified. However, there have been no reports to date regarding NECB with features of inflammatory breast carcinoma. Here, we describe the clinical, radiol-ogic, and pathologic findings of the first reported case of primary NECB presenting as inflammatory breast carcinoma. The patient complained of diffuse right breast enlargement and erythema. Mammography identified severe breast edema and axillary lymphadenopathy. Ultrasound detected an irregular, angular, hypoechoic mass with dermal lymphatic dilatation. On magnetic resonance imaging, the mass had rim enhancement and the entire right breast showed heterogeneous enhancement with malignant kinetic features. Pathology identified the mass as a primary NECB with positive for synaptophysin, CD56, estrogen and progesterone receptors.
| Original language | English |
|---|---|
| Pages (from-to) | 404-405 |
| Number of pages | 2 |
| Journal | Journal of Breast Cancer |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2015 Dec 1 |
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Keywords
- Breast neoplasms
- Magnetic resonance imaging
- Neuroendocrine carcinoma
- Ultrasonography
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Primary neuroendocrine carcinoma of the breast with clinical features of inflammatory breast carcinoma : A case report and literature review. / Lee, Do Hyung; Park, Ah Young; Seo, Bo Kyoung; Kim, Young Sik; Lee, Ki Yeol; Cha, Sang Hoon.
In: Journal of Breast Cancer, Vol. 18, No. 4, 01.12.2015, p. 404-405.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Primary neuroendocrine carcinoma of the breast with clinical features of inflammatory breast carcinoma
T2 - A case report and literature review
AU - Lee, Do Hyung
AU - Park, Ah Young
AU - Seo, Bo Kyoung
AU - Kim, Young Sik
AU - Lee, Ki Yeol
AU - Cha, Sang Hoon
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Primary neuroendocrine carcinoma of the breast (NECB) is a very rare type of invasive breast carcinoma. Most NECBs appear on breast imaging as solid masses of varied shapes and margins, and have worse clinical outcomes than does invasive ductal carcinoma, not otherwise specified. However, there have been no reports to date regarding NECB with features of inflammatory breast carcinoma. Here, we describe the clinical, radiol-ogic, and pathologic findings of the first reported case of primary NECB presenting as inflammatory breast carcinoma. The patient complained of diffuse right breast enlargement and erythema. Mammography identified severe breast edema and axillary lymphadenopathy. Ultrasound detected an irregular, angular, hypoechoic mass with dermal lymphatic dilatation. On magnetic resonance imaging, the mass had rim enhancement and the entire right breast showed heterogeneous enhancement with malignant kinetic features. Pathology identified the mass as a primary NECB with positive for synaptophysin, CD56, estrogen and progesterone receptors.
AB - Primary neuroendocrine carcinoma of the breast (NECB) is a very rare type of invasive breast carcinoma. Most NECBs appear on breast imaging as solid masses of varied shapes and margins, and have worse clinical outcomes than does invasive ductal carcinoma, not otherwise specified. However, there have been no reports to date regarding NECB with features of inflammatory breast carcinoma. Here, we describe the clinical, radiol-ogic, and pathologic findings of the first reported case of primary NECB presenting as inflammatory breast carcinoma. The patient complained of diffuse right breast enlargement and erythema. Mammography identified severe breast edema and axillary lymphadenopathy. Ultrasound detected an irregular, angular, hypoechoic mass with dermal lymphatic dilatation. On magnetic resonance imaging, the mass had rim enhancement and the entire right breast showed heterogeneous enhancement with malignant kinetic features. Pathology identified the mass as a primary NECB with positive for synaptophysin, CD56, estrogen and progesterone receptors.
KW - Breast neoplasms
KW - Magnetic resonance imaging
KW - Neuroendocrine carcinoma
KW - Ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=84957718308&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84957718308&partnerID=8YFLogxK
U2 - 10.4048/jbc.2015.18.4.404
DO - 10.4048/jbc.2015.18.4.404
M3 - Article
VL - 18
SP - 404
EP - 405
JO - Journal of Breast Cancer
JF - Journal of Breast Cancer
SN - 1738-6756
IS - 4
ER -