Abstract
Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
| Original language | English |
|---|---|
| Article number | e50939 |
| Journal | PLoS One |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2013 Jan 2 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
Cite this
Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects. / Xing, Wang; Nan, Chen; ZhenTao, Zuo; Rong, Xue; Luo, Jing; Zhuo, Yan; Shen, Dinggang; KunCheng, Li.
In: PLoS One, Vol. 8, No. 1, e50939, 02.01.2013.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects
AU - Xing, Wang
AU - Nan, Chen
AU - ZhenTao, Zuo
AU - Rong, Xue
AU - Luo, Jing
AU - Zhuo, Yan
AU - Shen, Dinggang
AU - KunCheng, Li
PY - 2013/1/2
Y1 - 2013/1/2
N2 - Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
AB - Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.
UR - http://www.scopus.com/inward/record.url?scp=84871738348&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84871738348&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0050939
DO - 10.1371/journal.pone.0050939
M3 - Article
C2 - 23341878
AN - SCOPUS:84871738348
VL - 8
JO - PLoS One
JF - PLoS One
SN - 1932-6203
IS - 1
M1 - e50939
ER -