Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects

Wang Xing, Chen Nan, Zuo ZhenTao, Xue Rong, Jing Luo, Yan Zhuo, Shen DingGang, Li KunCheng

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Brain atlases are designed to provide a standard reference coordinate system of the brain for neuroscience research. Existing human brain atlases are widely used to provide anatomical references and information regarding structural characteristics of the brain. The majority of them, however, are derived from one paticipant or small samples of the Western population. This poses a limitation for scientific studies on Eastern subjects. In this study, 10 new Chinese brain atlases for different ages and genders were constructed using MR anatomical images based on HAMMER (Hierarchical Attribute Matching Mechanism for Elastic Registration). A total of 1,000 Chinese volunteers ranging from 18 to 70 years old participated in this study. These population-specific brain atlases represent the basic structural characteristics of the Chinese population. They may be utilized for basic neuroscience studies and clinical diagnosis, including evaluation of neurological and neuropsychiatric disorders, in Chinese patients and those from other Eastern countries.

Original languageEnglish
Article numbere50939
JournalPloS one
Volume8
Issue number1
DOIs
Publication statusPublished - 2013 Jan 2

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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    Xing, W., Nan, C., ZhenTao, Z., Rong, X., Luo, J., Zhuo, Y., DingGang, S., & KunCheng, L. (2013). Probabilistic MRI Brain Anatomical Atlases Based on 1,000 Chinese Subjects. PloS one, 8(1), [e50939]. https://doi.org/10.1371/journal.pone.0050939