Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC

Ramesh Prasad Pandey, Prakash Parajuli, Niranjan Koirala, Je Won Park, Jae Kyung Sohng

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

Original languageEnglish
Pages (from-to)6833-6838
Number of pages6
JournalApplied and Environmental Microbiology
Volume79
Issue number21
DOIs
Publication statusPublished - 2013 Oct 25
Externally publishedYes

Fingerprint

Flavonols
flavonols
sugar
probe
myricetin
Diphosphates
Quercetin
kaempferol
glycosylation
Glycosylation
quercetin
Nucleotides
nucleotides
sugars
therapeutics
In Vitro Techniques
3-hydroxyflavone
Therapeutics

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Food Science
  • Biotechnology
  • Ecology

Cite this

Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC. / Pandey, Ramesh Prasad; Parajuli, Prakash; Koirala, Niranjan; Park, Je Won; Sohng, Jae Kyung.

In: Applied and Environmental Microbiology, Vol. 79, No. 21, 25.10.2013, p. 6833-6838.

Research output: Contribution to journalArticle

Pandey, Ramesh Prasad ; Parajuli, Prakash ; Koirala, Niranjan ; Park, Je Won ; Sohng, Jae Kyung. / Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC. In: Applied and Environmental Microbiology. 2013 ; Vol. 79, No. 21. pp. 6833-6838.
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