Probing 3-hydroxyflavone for In vitro glycorandomization of flavonols by YjiC

Ramesh Prasad Pandey, Prakash Parajuli, Niranjan Koirala, Je Won Park, Jae Kyung Sohng

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

The glycosylation of five different flavonols, fisetin, quercetin, myricetin, kaempferol, and 3-hydroxyflavone, was achieved by applying YjiC. 3-Hydroxyflavone was selected as a probe for in vitro glycorandomization of all flavonols using diverse nucleotide diphosphate-D/L-sugars. This study unlocked the possibilities of the glycodiversification of flavonols and the generation of novel compounds as future therapeutics.

Original languageEnglish
Pages (from-to)6833-6838
Number of pages6
JournalApplied and environmental microbiology
Volume79
Issue number21
DOIs
Publication statusPublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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