Abstract
Various strategies were studied to enhance 2,3-butanediol production using Enterobacter aerogenes SUMI014. The synergistic effect of acetate improved yield and productivity, and resulted in 32.3% increase in 2,3-butanediol production, compared to the wild strain. Optimizing the fermentation conditions successfully increased the 2,3-butanediol production. In batch fermentation, 93.75. g/L of 2,3-butanediol was obtained within 54. h, along with 0.49. g/g of yield and 1.74. g/L/h of productivity. The highest 2,3-butanediol production achieved was in fed-batch fermentation with acetate addition strategy, with production, yield and productivity of 126.10. g/L, 0.38. g/g and 2.10. g/L/h, respectively.
| Original language | English |
|---|---|
| Journal | Journal of Industrial and Engineering Chemistry |
| DOIs | |
| Publication status | Accepted/In press - 2017 |
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Keywords
- 2,3-Butanediol
- Acetate supplementation
- Enterobacter aerogenes
- Fermentation
- Lactate dehydrogenase
ASJC Scopus subject areas
- Chemical Engineering(all)
Cite this
Process strategy for 2,3-butanediol production in fed-batch culture by acetate addition. / Lee, Sang Jun; Choi, Han Suk; Kim, Chan Kyum; Thapa, Laxmi Prasad; Park, Chulhwan; Kim, Seung Wook.
In: Journal of Industrial and Engineering Chemistry, 2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Process strategy for 2,3-butanediol production in fed-batch culture by acetate addition
AU - Lee, Sang Jun
AU - Choi, Han Suk
AU - Kim, Chan Kyum
AU - Thapa, Laxmi Prasad
AU - Park, Chulhwan
AU - Kim, Seung Wook
PY - 2017
Y1 - 2017
N2 - Various strategies were studied to enhance 2,3-butanediol production using Enterobacter aerogenes SUMI014. The synergistic effect of acetate improved yield and productivity, and resulted in 32.3% increase in 2,3-butanediol production, compared to the wild strain. Optimizing the fermentation conditions successfully increased the 2,3-butanediol production. In batch fermentation, 93.75. g/L of 2,3-butanediol was obtained within 54. h, along with 0.49. g/g of yield and 1.74. g/L/h of productivity. The highest 2,3-butanediol production achieved was in fed-batch fermentation with acetate addition strategy, with production, yield and productivity of 126.10. g/L, 0.38. g/g and 2.10. g/L/h, respectively.
AB - Various strategies were studied to enhance 2,3-butanediol production using Enterobacter aerogenes SUMI014. The synergistic effect of acetate improved yield and productivity, and resulted in 32.3% increase in 2,3-butanediol production, compared to the wild strain. Optimizing the fermentation conditions successfully increased the 2,3-butanediol production. In batch fermentation, 93.75. g/L of 2,3-butanediol was obtained within 54. h, along with 0.49. g/g of yield and 1.74. g/L/h of productivity. The highest 2,3-butanediol production achieved was in fed-batch fermentation with acetate addition strategy, with production, yield and productivity of 126.10. g/L, 0.38. g/g and 2.10. g/L/h, respectively.
KW - 2,3-Butanediol
KW - Acetate supplementation
KW - Enterobacter aerogenes
KW - Fermentation
KW - Lactate dehydrogenase
UR - http://www.scopus.com/inward/record.url?scp=85025803252&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85025803252&partnerID=8YFLogxK
U2 - 10.1016/j.jiec.2017.07.008
DO - 10.1016/j.jiec.2017.07.008
M3 - Article
AN - SCOPUS:85025803252
JO - Journal of Industrial and Engineering Chemistry
JF - Journal of Industrial and Engineering Chemistry
SN - 1226-086X
ER -