TY - JOUR
T1 - Production and evaluation of porous titanium scaffolds with 3-dimensional periodic macrochannels coated with microporous TiO 2 layer
AU - Jung, Hyun Do
AU - Kim, Hyoun Ee
AU - Koh, Young Hag
N1 - Funding Information:
This research was supported by a grant from the Fundamental R&D Program for Core Technology of Materials funded by the Ministry of Knowledge Economy , Republic of Korea. (contract number : K00041294_15097).
PY - 2012/8/15
Y1 - 2012/8/15
N2 - This study examined the utility of a combination of the thermoplastic green machining (TGM) and micro-arc oxidation (MAO) for the production of porous Ti scaffolds with 3-dimensional (3-D) periodic macrochannels coated with a microporous TiO 2 layer, which would provide high mechanical properties and excellent biocompatibility simultaneously. The TGM technique allowed for the creation of tightly controlled 3-D periodic macrochannels with a diameter of ∼828-837 μm by machining a thermoplastic compound consisting of 70 vol% titanium hydride (TiH 2) powder and 30 vol% thermoplastic binders, followed by heat-treatment in a vacuum. The overall porosity and mechanical properties of the porous Ti scaffolds were controlled by creating various periodic arrays of 6 × 6, 7 × 7, or 8 × 8 macrochannels in each face of a cube. The compressive strength and modulus was decreased from 358 ± 7 to 100 ± 8 MPa and from 5.2 ± 0.66 to 3.5 ± 0.32 GPa, respectively, with increasing porosity from 48 vol% to 64 vol%. The biocompatibility and bioactivity, which was assessed by in vitro cellular assays, were improved remarkably by creating a microporous TiO 2 coating layer using the MAO treatment.
AB - This study examined the utility of a combination of the thermoplastic green machining (TGM) and micro-arc oxidation (MAO) for the production of porous Ti scaffolds with 3-dimensional (3-D) periodic macrochannels coated with a microporous TiO 2 layer, which would provide high mechanical properties and excellent biocompatibility simultaneously. The TGM technique allowed for the creation of tightly controlled 3-D periodic macrochannels with a diameter of ∼828-837 μm by machining a thermoplastic compound consisting of 70 vol% titanium hydride (TiH 2) powder and 30 vol% thermoplastic binders, followed by heat-treatment in a vacuum. The overall porosity and mechanical properties of the porous Ti scaffolds were controlled by creating various periodic arrays of 6 × 6, 7 × 7, or 8 × 8 macrochannels in each face of a cube. The compressive strength and modulus was decreased from 358 ± 7 to 100 ± 8 MPa and from 5.2 ± 0.66 to 3.5 ± 0.32 GPa, respectively, with increasing porosity from 48 vol% to 64 vol%. The biocompatibility and bioactivity, which was assessed by in vitro cellular assays, were improved remarkably by creating a microporous TiO 2 coating layer using the MAO treatment.
KW - Biomaterials
KW - Mechanical properties
KW - Metals
KW - Microporous materials
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U2 - 10.1016/j.matchemphys.2012.05.076
DO - 10.1016/j.matchemphys.2012.05.076
M3 - Article
AN - SCOPUS:84864715923
VL - 135
SP - 897
EP - 902
JO - Materials Chemistry and Physics
JF - Materials Chemistry and Physics
SN - 0254-0584
IS - 2-3
ER -