Prognostic importance of weight change on short-term functional outcome in acute ischemic stroke

Yerim Kim, Chi Kyung Kim, Seunguk Jung, Sang Bae Ko, Seung Hoon Lee, Byung Woo Yoon

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Controversy exists regarding the question of whether weight change decreases or increases the risk of mortality. Aim: The aim of this study was to evaluate the prognostic importance of weight change on short-term outcomes in acute ischemic stroke patients. Methods: A total of 654 patients with acute ischemic stroke were enrolled in this study from March 2010 to May 2013. We assessed the weight change of each participant between admission and discharge from the Department of Neurology. Weight change was defined as change ≥0·05kg/baseline body mass index unit. We evaluated the short-term outcomes using a modified Rankin Scale at three-months after the onset of a stroke. Results: Among the 654 patients, 35·2% were included in the weight-change group. Weight loss occurred in 24·6% of the participants during the hospital stay following the stroke, which lasted an average of nine-days. Compared with the weight-stable group, the pronounced weight-loss group had a higher risk of unfavorable outcomes (odds ratio 2·43; 95% confidence interval 1·12-5·25). Conclusions: Short-term weight loss after stroke appears to be more common than we expected, and our results suggest that it is associated with unfavorable functional outcomes. Therefore, clinical nutrition should be considered as a component of medical treatment and weight loss should be monitored as an indicator of malnutrition.

Original languageEnglish
Pages (from-to)62-68
Number of pages7
JournalInternational Journal of Stroke
Volume10
Issue numberA100
DOIs
Publication statusPublished - 2015 Oct 1
Externally publishedYes

Fingerprint

Stroke
Weights and Measures
Weight Loss
Neurology
Malnutrition
Length of Stay
Body Mass Index
Odds Ratio
Confidence Intervals
Mortality
Therapeutics

Keywords

  • Body mass index
  • Cerebral infarction
  • Ischemic stroke
  • Outcome
  • Stroke

ASJC Scopus subject areas

  • Neurology

Cite this

Prognostic importance of weight change on short-term functional outcome in acute ischemic stroke. / Kim, Yerim; Kim, Chi Kyung; Jung, Seunguk; Ko, Sang Bae; Lee, Seung Hoon; Yoon, Byung Woo.

In: International Journal of Stroke, Vol. 10, No. A100, 01.10.2015, p. 62-68.

Research output: Contribution to journalArticle

Kim, Yerim ; Kim, Chi Kyung ; Jung, Seunguk ; Ko, Sang Bae ; Lee, Seung Hoon ; Yoon, Byung Woo. / Prognostic importance of weight change on short-term functional outcome in acute ischemic stroke. In: International Journal of Stroke. 2015 ; Vol. 10, No. A100. pp. 62-68.
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