Proposal for genetic characterisation of wild-type mumps strains

Preliminary standardisation of the nomenclature

L. Jin, B. Rima, D. Brown, C. Örvell, T. Tecle, M. Afzal, K. Uchida, T. Nakayama, Jin Won Song, C. Kang, P. A. Rota, W. Xu, D. Featherstone

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Though mumps virus (MuV) is a monotypic virus, genetic variation between strains has been described. Viruses have been placed into genotypes designated A-L based on the nucleotide sequence of the small hydrophobic (SH) gene, which is the most variable gene in the mumps genome. Molecular characterisation of MuV is an important component of mumps surveillance because it can help identify the transmission pathways of the virus as well as distinguish between wild-type and vaccine strains. Here, we propose a standardized nomenclature and an analysis protocol for the genetic characterisation of mumps strains to facilitate expansion of molecular epidemiological studies. In addition to assigning standard reference strains for the recognized genotypes of MuV, a convention is proposed for naming for strains and criteria to designate a new genotype.

Original languageEnglish
Pages (from-to)1903-1909
Number of pages7
JournalArchives of Virology
Volume150
Issue number9
DOIs
Publication statusPublished - 2005 Aug 1

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Mumps virus
Mumps
Terminology
Viruses
Standardization
Genotype
Genes
Epidemiologic Studies
Vaccines
Genome
Nucleotides

ASJC Scopus subject areas

  • Genetics
  • Applied Microbiology and Biotechnology

Cite this

Jin, L., Rima, B., Brown, D., Örvell, C., Tecle, T., Afzal, M., ... Featherstone, D. (2005). Proposal for genetic characterisation of wild-type mumps strains: Preliminary standardisation of the nomenclature. Archives of Virology, 150(9), 1903-1909. https://doi.org/10.1007/s00705-005-0563-4

Proposal for genetic characterisation of wild-type mumps strains : Preliminary standardisation of the nomenclature. / Jin, L.; Rima, B.; Brown, D.; Örvell, C.; Tecle, T.; Afzal, M.; Uchida, K.; Nakayama, T.; Song, Jin Won; Kang, C.; Rota, P. A.; Xu, W.; Featherstone, D.

In: Archives of Virology, Vol. 150, No. 9, 01.08.2005, p. 1903-1909.

Research output: Contribution to journalArticle

Jin, L, Rima, B, Brown, D, Örvell, C, Tecle, T, Afzal, M, Uchida, K, Nakayama, T, Song, JW, Kang, C, Rota, PA, Xu, W & Featherstone, D 2005, 'Proposal for genetic characterisation of wild-type mumps strains: Preliminary standardisation of the nomenclature', Archives of Virology, vol. 150, no. 9, pp. 1903-1909. https://doi.org/10.1007/s00705-005-0563-4
Jin, L. ; Rima, B. ; Brown, D. ; Örvell, C. ; Tecle, T. ; Afzal, M. ; Uchida, K. ; Nakayama, T. ; Song, Jin Won ; Kang, C. ; Rota, P. A. ; Xu, W. ; Featherstone, D. / Proposal for genetic characterisation of wild-type mumps strains : Preliminary standardisation of the nomenclature. In: Archives of Virology. 2005 ; Vol. 150, No. 9. pp. 1903-1909.
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