Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model

Eunmi Kim, Dong Won Lee, Hae Chul Park, Dong Hwee Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.

Original languageEnglish
Article number100783
JournalMolecular Genetics and Metabolism Reports
Volume28
DOIs
Publication statusPublished - 2021 Sep

Keywords

  • Alpha-lipoic acid
  • Diabetes mellitus
  • Hair cell
  • Pancreatic β-cell
  • Zebrafish

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Endocrinology

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