Protein Recognition by Phase Transition of Aptamer-Linked Polythiophene Single Nanowire

Chunzhi Cui; Dong Hyuk Park; Hyun Choi; Jinsoo Joo; Dong June Ahn

doi:10.1002/smll.201501908

Protein Recognition by Phase Transition of Aptamer-Linked Polythiophene Single Nanowire

Chunzhi Cui, Dong Hyuk Park, Hyun Choi, Jinsoo Joo, Dong June Ahn

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A novel protein recognition platform is developed using aptamer-linked polythiophene nanowires. As the aptamer functionalized poly (3-methylthiophene) nanowire is treated by the specific protein, resonance Raman and photoluminescence signals are simultaneously enhanced. Statistical analyses deliver the capability of a single conjugated polymer nanowire with phase-transition characteristics in response to selectivity and concentration.

Original language	English
Pages (from-to)	1154-1158
Number of pages	5
Journal	Small
Volume	12
Issue number	9
DOIs	https://doi.org/10.1002/smll.201501908
Publication status	Published - 2016 Mar 2

Keywords

aptamer-linked polythiophene
direct protein recognition
phase-transition nanowires

ASJC Scopus subject areas

Biotechnology
Biomaterials
Chemistry(all)
Materials Science(all)

Access to Document

10.1002/smll.201501908

Cite this

@article{9384d35b25c94373a5895848f93c58b7,

title = "Protein Recognition by Phase Transition of Aptamer-Linked Polythiophene Single Nanowire",

abstract = "A novel protein recognition platform is developed using aptamer-linked polythiophene nanowires. As the aptamer functionalized poly (3-methylthiophene) nanowire is treated by the specific protein, resonance Raman and photoluminescence signals are simultaneously enhanced. Statistical analyses deliver the capability of a single conjugated polymer nanowire with phase-transition characteristics in response to selectivity and concentration.",

keywords = "aptamer-linked polythiophene, direct protein recognition, phase-transition nanowires",

author = "Chunzhi Cui and Park, {Dong Hyuk} and Hyun Choi and Jinsoo Joo and Ahn, {Dong June}",

note = "Funding Information: C.C., D.H.P., and H.C. contributed equally to this work. D.J.A. acknowledges support from the National Research Foundation (MSIP 2014023305, 2015M3C1A3002152), KU‐KIST Graduate School of Converging Science and Technology (R1309521), and a Korea University Grant. J.J. acknowledges support from the Global Frontier Project (CAMM‐2014M3A6B3063710) by MSIP, Korea. Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",

year = "2016",

month = mar,

day = "2",

doi = "10.1002/smll.201501908",

language = "English",

volume = "12",

pages = "1154--1158",

journal = "Small",

issn = "1613-6810",

publisher = "Wiley-VCH Verlag",

number = "9",

}

TY - JOUR

T1 - Protein Recognition by Phase Transition of Aptamer-Linked Polythiophene Single Nanowire

AU - Cui, Chunzhi

AU - Park, Dong Hyuk

AU - Choi, Hyun

AU - Joo, Jinsoo

AU - Ahn, Dong June

N1 - Funding Information: C.C., D.H.P., and H.C. contributed equally to this work. D.J.A. acknowledges support from the National Research Foundation (MSIP 2014023305, 2015M3C1A3002152), KU‐KIST Graduate School of Converging Science and Technology (R1309521), and a Korea University Grant. J.J. acknowledges support from the Global Frontier Project (CAMM‐2014M3A6B3063710) by MSIP, Korea. Publisher Copyright: © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.

PY - 2016/3/2

Y1 - 2016/3/2

N2 - A novel protein recognition platform is developed using aptamer-linked polythiophene nanowires. As the aptamer functionalized poly (3-methylthiophene) nanowire is treated by the specific protein, resonance Raman and photoluminescence signals are simultaneously enhanced. Statistical analyses deliver the capability of a single conjugated polymer nanowire with phase-transition characteristics in response to selectivity and concentration.

AB - A novel protein recognition platform is developed using aptamer-linked polythiophene nanowires. As the aptamer functionalized poly (3-methylthiophene) nanowire is treated by the specific protein, resonance Raman and photoluminescence signals are simultaneously enhanced. Statistical analyses deliver the capability of a single conjugated polymer nanowire with phase-transition characteristics in response to selectivity and concentration.

KW - aptamer-linked polythiophene

KW - direct protein recognition

KW - phase-transition nanowires

UR - http://www.scopus.com/inward/record.url?scp=84960125732&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84960125732&partnerID=8YFLogxK

U2 - 10.1002/smll.201501908

DO - 10.1002/smll.201501908

M3 - Article

C2 - 26651134

AN - SCOPUS:84960125732

SN - 1613-6810

VL - 12

SP - 1154

EP - 1158

JO - Small

JF - Small

IS - 9

ER -

Protein Recognition by Phase Transition of Aptamer-Linked Polythiophene Single Nanowire

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this