Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044

Sang Un Lee, Yukihiro Asami, Dongho Lee, Jae Hyuk Jang, Jong Seog Ahn, Hyuncheol Oh

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Two new oxepin-containing (1 and 2) and two diketopiperazine-type alkaloids (3 and 4) have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044. The structures of these metabolites were determined through analysis of NMR and MS data, along with Marfey's method. Compound 1 showed weak growth inhibitory activity against a small panel of cell lines. (Chemical Equation Presented).

Original languageEnglish
Pages (from-to)1284-1287
Number of pages4
JournalJournal of Natural Products
Volume74
Issue number5
DOIs
Publication statusPublished - 2011 May 27

Fingerprint

Oxepins
Diketopiperazines
Aspergillus
Metabolites
Fungi
Alkaloids
Cells
Nuclear magnetic resonance
Cell Line
Growth
protuboxepin A
protuboxepin B
protubonine B
protubonine A

ASJC Scopus subject areas

  • Complementary and alternative medicine
  • Molecular Medicine
  • Organic Chemistry
  • Analytical Chemistry
  • Pharmaceutical Science
  • Pharmacology
  • Drug Discovery

Cite this

Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044. / Lee, Sang Un; Asami, Yukihiro; Lee, Dongho; Jang, Jae Hyuk; Ahn, Jong Seog; Oh, Hyuncheol.

In: Journal of Natural Products, Vol. 74, No. 5, 27.05.2011, p. 1284-1287.

Research output: Contribution to journalArticle

Lee, Sang Un ; Asami, Yukihiro ; Lee, Dongho ; Jang, Jae Hyuk ; Ahn, Jong Seog ; Oh, Hyuncheol. / Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044. In: Journal of Natural Products. 2011 ; Vol. 74, No. 5. pp. 1284-1287.
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