Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta

Joong Yull Park; Chan Young Park; Chang Mo Hwang; Kyung Sun; Byoung Goo Min

doi:10.1016/j.compbiomed.2006.09.012

Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta

Joong Yull Park, Chan Young Park, Chang Mo Hwang, Kyung Sun, Byoung Goo Min

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

In three-dimensional numerical studies of the aorta, it is difficult to apply proper boundary conditions at the end of each major aortic branch because of interactions between blood and organs. Organs and body parts were assumed to be likened to cylindrically shaped porous media, so-called pseudo-organs, and treated in the computational domain as forms of hemodynamic resistance. Permeability functions were determined from two-dimensional axisymmetric computations of each aortic branch and these functions were then used in an unsteady three-dimensional simulation of the complete aorta. Substantially accurate cardiac output (5.91 L/min) and blood distributions to the major branches were predicted.

Original language	English
Pages (from-to)	1063-1072
Number of pages	10
Journal	Computers in Biology and Medicine
Volume	37
Issue number	8
DOIs	https://doi.org/10.1016/j.compbiomed.2006.09.012
Publication status	Published - 2007 Aug
Externally published	Yes

Keywords

Aorta
Blood interaction
Hemodynamic resistance
Numerical analysis
Porous media

ASJC Scopus subject areas

Computer Science Applications
Health Informatics

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10.1016/j.compbiomed.2006.09.012

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title = "Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta",

abstract = "In three-dimensional numerical studies of the aorta, it is difficult to apply proper boundary conditions at the end of each major aortic branch because of interactions between blood and organs. Organs and body parts were assumed to be likened to cylindrically shaped porous media, so-called pseudo-organs, and treated in the computational domain as forms of hemodynamic resistance. Permeability functions were determined from two-dimensional axisymmetric computations of each aortic branch and these functions were then used in an unsteady three-dimensional simulation of the complete aorta. Substantially accurate cardiac output (5.91 L/min) and blood distributions to the major branches were predicted.",

keywords = "Aorta, Blood interaction, Hemodynamic resistance, Numerical analysis, Porous media",

author = "{Yull Park}, Joong and {Young Park}, Chan and {Mo Hwang}, Chang and Kyung Sun and {Goo Min}, Byoung",

note = "Funding Information: Kyung Sun Professor of Korea University Medical School, was born in Seoul, Korea. He is a chief of Biomedical Engineering as well as a chair of Thoracic and Cardiovascular Surgery at Korea University. In 2003, he has founded Korea Artificial Organ Center which is funded by Ministry of Health of Korean government. His main clinical activities are adult cardiac surgery including CABG and valve operation, and the main research interests are artificial organs, especially artificial heart for either preclinical orclinical trial. Funding Information: This study was supported by the grant from the Korea Health 21 R&D Project of the Ministry of Health & Welfare (grant no. A020609) and the Brain Korea 21 Project of the Ministry of Education and Human Resources Development, Republic of Korea. C.Y. Park was supported by the Post-doctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF). ",

year = "2007",

month = aug,

doi = "10.1016/j.compbiomed.2006.09.012",

language = "English",

volume = "37",

pages = "1063--1072",

journal = "Computers in Biology and Medicine",

issn = "0010-4825",

publisher = "Elsevier Limited",

number = "8",

}

TY - JOUR

T1 - Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta

AU - Yull Park, Joong

AU - Young Park, Chan

AU - Mo Hwang, Chang

AU - Sun, Kyung

AU - Goo Min, Byoung

N1 - Funding Information: Kyung Sun Professor of Korea University Medical School, was born in Seoul, Korea. He is a chief of Biomedical Engineering as well as a chair of Thoracic and Cardiovascular Surgery at Korea University. In 2003, he has founded Korea Artificial Organ Center which is funded by Ministry of Health of Korean government. His main clinical activities are adult cardiac surgery including CABG and valve operation, and the main research interests are artificial organs, especially artificial heart for either preclinical orclinical trial. Funding Information: This study was supported by the grant from the Korea Health 21 R&D Project of the Ministry of Health & Welfare (grant no. A020609) and the Brain Korea 21 Project of the Ministry of Education and Human Resources Development, Republic of Korea. C.Y. Park was supported by the Post-doctoral Fellowship Program of Korea Science & Engineering Foundation (KOSEF).

PY - 2007/8

Y1 - 2007/8

N2 - In three-dimensional numerical studies of the aorta, it is difficult to apply proper boundary conditions at the end of each major aortic branch because of interactions between blood and organs. Organs and body parts were assumed to be likened to cylindrically shaped porous media, so-called pseudo-organs, and treated in the computational domain as forms of hemodynamic resistance. Permeability functions were determined from two-dimensional axisymmetric computations of each aortic branch and these functions were then used in an unsteady three-dimensional simulation of the complete aorta. Substantially accurate cardiac output (5.91 L/min) and blood distributions to the major branches were predicted.

AB - In three-dimensional numerical studies of the aorta, it is difficult to apply proper boundary conditions at the end of each major aortic branch because of interactions between blood and organs. Organs and body parts were assumed to be likened to cylindrically shaped porous media, so-called pseudo-organs, and treated in the computational domain as forms of hemodynamic resistance. Permeability functions were determined from two-dimensional axisymmetric computations of each aortic branch and these functions were then used in an unsteady three-dimensional simulation of the complete aorta. Substantially accurate cardiac output (5.91 L/min) and blood distributions to the major branches were predicted.

KW - Aorta

KW - Blood interaction

KW - Hemodynamic resistance

KW - Numerical analysis

KW - Porous media

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M3 - Article

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AN - SCOPUS:34250838008

VL - 37

SP - 1063

EP - 1072

JO - Computers in Biology and Medicine

JF - Computers in Biology and Medicine

SN - 0010-4825

IS - 8

ER -

Pseudo-organ boundary conditions applied to a computational fluid dynamics model of the human aorta

Abstract

Keywords

ASJC Scopus subject areas

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