Pt-catalyzed hydrative cyclization of 2-enynylbenzaldehydes and its application to faveline synthesis

Chang Ho Oh, Sung Min Lee, Chang Seop Hong

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37 Citations (Scopus)

Abstract

"Chemical Equation Presented" Various 2-[6-en-1-ynyl] benzaldehydes and their analogues were successfully cyclized via Huisgen-type [3+2] cycloaddition to the tetracyclic platinum-carbene complex, which would subsequently undergo hydration to afford the tricyclic products in good yields with excellent stereoselectivities. This hydrative cyclization was also applied to the faveline synthesis.

Original languageEnglish
Pages (from-to)1308-1311
Number of pages4
JournalOrganic Letters
Volume12
Issue number6
DOIs
Publication statusPublished - 2010 Mar 19

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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