Pulmonary function changes over 1 year after lobectomy in lung cancer

Hyun Koo Kim, Yoo Jin Lee, Kook Nam Han, Young Ho Choi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

BACKGROUND: This study was conducted to measure the serial changes in pulmonary function over 12 months after lobectomy in subjects with lung cancer and to evaluate the actual recovery of pulmonary function in comparison with the predicted postoperative values. METHODS: Subjects who underwent lobectomy for primary lung cancer were included in this study. In the statistical analysis, we included data from 76 subjects (52 men and 24 women; mean age, 63.4 y) who completed perfusion scintigraphy 1 week before surgery and FEV1 and diffusion capacity of the lung for carbon monoxide (DLCO) assessments preoperatively and at 1, 6, and 12 months postoperatively. RESULTS: The actual percent-of-predicted FEV1 1 month postoperatively was 77.9% of the preoperative value, which was almost equal to the predicted postoperative value, and significantly increased to 84.3% by 6 months and 84.2% at 12 months. The actual percent-of-predicted DLCO 1 month postoperatively was 81.8% of the preoperative value, which was similar to the predicted postoperative value, and also significantly increased to 91.3% at 6 months and 96.5% at 12 months. However, the actual pulmonary function test results at 1 y in subjects with COPD or in those who underwent thoracotomy or received adjuvant chemotherapy were not different from the predicted postoperative values. CONCLUSIONS: Actual pulmonary function compared with predicted postoperative values improved over time over 1 y after lobectomy. However, this improvement was not observed in subjects with COPD or in those who underwent thoracotomy or received postoperative adjuvant chemotherapy.

Original languageEnglish
Pages (from-to)376-382
Number of pages7
JournalRespiratory Care
Volume61
Issue number3
DOIs
Publication statusPublished - 2016 Mar 1

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Lung Neoplasms
Thoracotomy
Adjuvant Chemotherapy
Lung
Chronic Obstructive Pulmonary Disease
Lung Volume Measurements
Perfusion Imaging
Respiratory Function Tests
Recovery of Function
Carbon Monoxide

Keywords

  • Lobectomy
  • Lung cancer
  • Pulmonary function

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Pulmonary function changes over 1 year after lobectomy in lung cancer. / Kim, Hyun Koo ; Lee, Yoo Jin; Han, Kook Nam; Choi, Young Ho.

In: Respiratory Care, Vol. 61, No. 3, 01.03.2016, p. 376-382.

Research output: Contribution to journalArticle

Kim, Hyun Koo ; Lee, Yoo Jin ; Han, Kook Nam ; Choi, Young Ho. / Pulmonary function changes over 1 year after lobectomy in lung cancer. In: Respiratory Care. 2016 ; Vol. 61, No. 3. pp. 376-382.
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