Purple glove syndrome caused by intravenous phenytoin injection

Won Ung Shin, Hae Jun Song

Research output: Contribution to journalArticlepeer-review


Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that is poorly understood and potentially serious. The characteristic features of PGS are pain, edema, and discoloration at the injection site that spreads to the distal limbs. Diagnosis of PGS can be made from clinical presentation, and treatment is usually restricted to conservative therapy. A 7-year-old girl was treated with phenytoin for epilepsy and was referred to our department for violaceous color change and edema on intravenous injection site of the left hand. It was consistent with PGS, and to our knowledge, it is first report in Korea.

Original languageEnglish
Pages (from-to)1038-1040
Number of pages3
JournalKorean Journal of Dermatology
Issue number11
Publication statusPublished - 2011 Nov


  • Phenytoin
  • Purple glove syndrome

ASJC Scopus subject areas

  • Dermatology


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