[Q fever as a cause of acute hepatitis accompanying fever].

Hyun Jung Lee, Ji Hoon Kim, Eileen L. Yoon, Young-Sun Lee, Jong Eun Yeon, Kwan Soo Byun, Baek-Hui Kim, Youngjoon Ryu

Research output: Contribution to journalArticle

Abstract

Q fever is a zoonotic infection caused by Coxiella burnetti, which has been previously regarded as an uncommon infectious disease in Korea but is sporadically reported recently. Common manifestations of acute Q fever usually present as influenza-like illness, pneumonia and occasionally hepatitis. Herein, we report 4 cases of acute Q fever as a cause of acute hepatitis and fever. All patients had fever and non-specific symptoms, and laboratory test showed acute hepatitis. Antibody surveys for many virus infections and bacterial cultures were negative. Finally, they were diagnosed acute Q fever by an indirect microimmunofluorescence test. Liver biopsy in 3 patients revealed granuloma including one with typical fibrin-ring. All patients had complete resolution of symptoms and signs with doxycycline treatment. Q fever should be considered in the differential diagnosis of patients with fever of unknown origin with acute hepatitis in Korea.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume57
Issue number3
DOIs
Publication statusPublished - 2011 Mar 25

Fingerprint

Q Fever
Hepatitis
Fever
Korea
Coxiella
Fever of Unknown Origin
Doxycycline
Zoonoses
Virus Diseases
Granuloma
Fibrin
Human Influenza
Signs and Symptoms
Communicable Diseases
Pneumonia
Differential Diagnosis
Biopsy
Antibodies
Liver

ASJC Scopus subject areas

  • Medicine(all)

Cite this

[Q fever as a cause of acute hepatitis accompanying fever]. / Lee, Hyun Jung; Kim, Ji Hoon; Yoon, Eileen L.; Lee, Young-Sun; Yeon, Jong Eun; Byun, Kwan Soo; Kim, Baek-Hui; Ryu, Youngjoon.

In: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, Vol. 57, No. 3, 25.03.2011, p. 189-193.

Research output: Contribution to journalArticle

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