Quality of life after endoscopic submucosal dissection for early gastric cancer

A prospective multicenter cohort study

Sang Gyun Kim, Seon Mi Ji, Na Rae Lee, Seung Hee Park, Ji Hye You, Il Ju Choi, Wan Sik Lee, Seun Ja Park, Jun Haeng Lee, Sang Yong Seol, Ji Hyun Kim, Chul Hyun Lim, Joo Young Cho, Gwang Ha Kim, Hoon-Jai Chun, Yong Chan Lee, Hwoon Yong Jung, Jae J. Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.

Original languageEnglish
Pages (from-to)87-92
Number of pages6
JournalGut and Liver
Volume11
Issue number1
DOIs
Publication statusPublished - 2017 Jan 1

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Multicenter Studies
Stomach Neoplasms
Cohort Studies
Quality of Life
Organizations
Endoscopic Mucosal Resection
Research
Health Status
Neoplasms
Therapeutics

Keywords

  • Early gastric cancer
  • Endoscopic submucosal dissection
  • Quality of life

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Kim, S. G., Ji, S. M., Lee, N. R., Park, S. H., You, J. H., Choi, I. J., ... Kim, J. J. (2017). Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study. Gut and Liver, 11(1), 87-92. https://doi.org/10.5009/gnl15549

Quality of life after endoscopic submucosal dissection for early gastric cancer : A prospective multicenter cohort study. / Kim, Sang Gyun; Ji, Seon Mi; Lee, Na Rae; Park, Seung Hee; You, Ji Hye; Choi, Il Ju; Lee, Wan Sik; Park, Seun Ja; Lee, Jun Haeng; Seol, Sang Yong; Kim, Ji Hyun; Lim, Chul Hyun; Cho, Joo Young; Kim, Gwang Ha; Chun, Hoon-Jai; Lee, Yong Chan; Jung, Hwoon Yong; Kim, Jae J.

In: Gut and Liver, Vol. 11, No. 1, 01.01.2017, p. 87-92.

Research output: Contribution to journalArticle

Kim, SG, Ji, SM, Lee, NR, Park, SH, You, JH, Choi, IJ, Lee, WS, Park, SJ, Lee, JH, Seol, SY, Kim, JH, Lim, CH, Cho, JY, Kim, GH, Chun, H-J, Lee, YC, Jung, HY & Kim, JJ 2017, 'Quality of life after endoscopic submucosal dissection for early gastric cancer: A prospective multicenter cohort study', Gut and Liver, vol. 11, no. 1, pp. 87-92. https://doi.org/10.5009/gnl15549
Kim, Sang Gyun ; Ji, Seon Mi ; Lee, Na Rae ; Park, Seung Hee ; You, Ji Hye ; Choi, Il Ju ; Lee, Wan Sik ; Park, Seun Ja ; Lee, Jun Haeng ; Seol, Sang Yong ; Kim, Ji Hyun ; Lim, Chul Hyun ; Cho, Joo Young ; Kim, Gwang Ha ; Chun, Hoon-Jai ; Lee, Yong Chan ; Jung, Hwoon Yong ; Kim, Jae J. / Quality of life after endoscopic submucosal dissection for early gastric cancer : A prospective multicenter cohort study. In: Gut and Liver. 2017 ; Vol. 11, No. 1. pp. 87-92.
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abstract = "Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.",
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T1 - Quality of life after endoscopic submucosal dissection for early gastric cancer

T2 - A prospective multicenter cohort study

AU - Kim, Sang Gyun

AU - Ji, Seon Mi

AU - Lee, Na Rae

AU - Park, Seung Hee

AU - You, Ji Hye

AU - Choi, Il Ju

AU - Lee, Wan Sik

AU - Park, Seun Ja

AU - Lee, Jun Haeng

AU - Seol, Sang Yong

AU - Kim, Ji Hyun

AU - Lim, Chul Hyun

AU - Cho, Joo Young

AU - Kim, Gwang Ha

AU - Chun, Hoon-Jai

AU - Lee, Yong Chan

AU - Jung, Hwoon Yong

AU - Kim, Jae J.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Background/Aims: Endoscopic submucosal dissection (ESD) has been an established treatment for indicated early gastric cancer (EGC) without deterioration of quality of life (QOL) compared with surgical resection. The aim of this study was to evaluate long-term QOL in patients undergoing ESD for EGC. Methods: Patients scheduled to undergo curative ESD for EGC were prospectively enrolled from 12 institutions between May 2010 and December 2011. Assessments of QOL with Korean versions of the European Organization for Research and Treatment of Cancer (EORTC) QOL questionnaire-core (QLQ-C30) and a gastric cancer-specific questionnaire (STO22) were performed at baseline and at 7 days, 3 months, and 6 months after ESD. Results: A total of 666 subjects were assessed for QLQ-C30 and QLQ-STO22. The mean QLQ-C30 score was 69.5 at baseline, 68.8 at 7 days, 73.1 at 3 months, and 73.2 at 6 months. The global health status on the EORTC QLQ-C30 was significantly improved after 3 and 6 months (p=0.0003 and p<0.0001, respectively). The QLQ-C30 and STO22 scores were not significantly different, or they only slightly deteriorated between before and immediately after ESD, but they were significantly improved after 3 and 6 months (p<0.05). Conclusions: QOL did not deteriorate immediately after ESD, and it improved more significantly at up to 6 months in patients who underwent curative ESD for EGC without significant complications.

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