Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy

Yeonho Choi, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We demonstrate the dual mode quantification method of Amyloid-β fibrilization using dark-field optical imaging and dielectric relaxation spectroscopy. Optically transparent sub-micron gap microfluidic electrode is designed to observe the change of hydrodynamic radius during the process of Amyloid-β fibrilization and correlated the hydrodynamic radius via dual mode measurements.

Original languageEnglish
Title of host publication12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference
PublisherChemical and Biological Microsystems Society
Pages342-344
Number of pages3
Publication statusPublished - 2008 Jan 1
Externally publishedYes
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: 2008 Oct 122008 Oct 16

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period08/10/1208/10/16

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ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

Cite this

Choi, Y., & Lee, L. P. (2008). Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy. In 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference (pp. 342-344). Chemical and Biological Microsystems Society.