Quantification of bradykinesia during clinical finger taps using a gyrosensor in patients with Parkinson's disease

Ji Won Kim, Jae Ho Lee, Yuri Kwon, Chul Seung Kim, Gwang Moon Eom, Seong Beom Koh, Do-Young Kwon, Kun Woo Park

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

This study aims to develop a quantitative measure of bradykinesia which can be conveniently used during clinical finger taps test in patients with Parkinson's disease. A miniature, light-weight gyrosensor free from gravitational artifact was used for measurement of finger taps in order to impose minimal constraint on patients. Forty Parkinson's disease patients and 14 age-matched control subjects participated in the experiments. Subjects' finger taps in both right and left hands were scored by two independent neurologists according to the unified Parkinson's disease rating scale and were also measured by a gyrosensor. Four performance indices were derived from the gyrosensor signal of the index finger. All indices showed significant differences between control and patients (P < 0.001) and also significant correlations with the clinical finger taps score (r = -0.73 to -0.80, P < 0.001). ANOVA showed significant differences in all indices among different finger taps scores (P < 0.001), and post hoc tests showed significant differences in indices between most pairs of non-neighboring and part of neighboring pairs of finger taps scores (P < 0.01). The results suggest that indices from a gyrosensor can be used as quantitative measures of bradykinesia during the finger taps test.

Original languageEnglish
Pages (from-to)365-371
Number of pages7
JournalMedical and Biological Engineering and Computing
Volume49
Issue number3
DOIs
Publication statusPublished - 2011 Mar 1

Fingerprint

Analysis of variance (ANOVA)
Experiments

Keywords

  • Bradykinesia
  • Finger taps
  • Gyrosensor
  • Parkinson's disease
  • Quantification
  • UPDRS

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Science Applications

Cite this

Quantification of bradykinesia during clinical finger taps using a gyrosensor in patients with Parkinson's disease. / Kim, Ji Won; Lee, Jae Ho; Kwon, Yuri; Kim, Chul Seung; Eom, Gwang Moon; Koh, Seong Beom; Kwon, Do-Young; Park, Kun Woo.

In: Medical and Biological Engineering and Computing, Vol. 49, No. 3, 01.03.2011, p. 365-371.

Research output: Contribution to journalArticle

@article{5896041214a349b882dfb15ee2c5335b,
title = "Quantification of bradykinesia during clinical finger taps using a gyrosensor in patients with Parkinson's disease",
abstract = "This study aims to develop a quantitative measure of bradykinesia which can be conveniently used during clinical finger taps test in patients with Parkinson's disease. A miniature, light-weight gyrosensor free from gravitational artifact was used for measurement of finger taps in order to impose minimal constraint on patients. Forty Parkinson's disease patients and 14 age-matched control subjects participated in the experiments. Subjects' finger taps in both right and left hands were scored by two independent neurologists according to the unified Parkinson's disease rating scale and were also measured by a gyrosensor. Four performance indices were derived from the gyrosensor signal of the index finger. All indices showed significant differences between control and patients (P < 0.001) and also significant correlations with the clinical finger taps score (r = -0.73 to -0.80, P < 0.001). ANOVA showed significant differences in all indices among different finger taps scores (P < 0.001), and post hoc tests showed significant differences in indices between most pairs of non-neighboring and part of neighboring pairs of finger taps scores (P < 0.01). The results suggest that indices from a gyrosensor can be used as quantitative measures of bradykinesia during the finger taps test.",
keywords = "Bradykinesia, Finger taps, Gyrosensor, Parkinson's disease, Quantification, UPDRS",
author = "Kim, {Ji Won} and Lee, {Jae Ho} and Yuri Kwon and Kim, {Chul Seung} and Eom, {Gwang Moon} and Koh, {Seong Beom} and Do-Young Kwon and Park, {Kun Woo}",
year = "2011",
month = "3",
day = "1",
doi = "10.1007/s11517-010-0697-8",
language = "English",
volume = "49",
pages = "365--371",
journal = "Medical and Biological Engineering and Computing",
issn = "0140-0118",
publisher = "Springer Verlag",
number = "3",

}

TY - JOUR

T1 - Quantification of bradykinesia during clinical finger taps using a gyrosensor in patients with Parkinson's disease

AU - Kim, Ji Won

AU - Lee, Jae Ho

AU - Kwon, Yuri

AU - Kim, Chul Seung

AU - Eom, Gwang Moon

AU - Koh, Seong Beom

AU - Kwon, Do-Young

AU - Park, Kun Woo

PY - 2011/3/1

Y1 - 2011/3/1

N2 - This study aims to develop a quantitative measure of bradykinesia which can be conveniently used during clinical finger taps test in patients with Parkinson's disease. A miniature, light-weight gyrosensor free from gravitational artifact was used for measurement of finger taps in order to impose minimal constraint on patients. Forty Parkinson's disease patients and 14 age-matched control subjects participated in the experiments. Subjects' finger taps in both right and left hands were scored by two independent neurologists according to the unified Parkinson's disease rating scale and were also measured by a gyrosensor. Four performance indices were derived from the gyrosensor signal of the index finger. All indices showed significant differences between control and patients (P < 0.001) and also significant correlations with the clinical finger taps score (r = -0.73 to -0.80, P < 0.001). ANOVA showed significant differences in all indices among different finger taps scores (P < 0.001), and post hoc tests showed significant differences in indices between most pairs of non-neighboring and part of neighboring pairs of finger taps scores (P < 0.01). The results suggest that indices from a gyrosensor can be used as quantitative measures of bradykinesia during the finger taps test.

AB - This study aims to develop a quantitative measure of bradykinesia which can be conveniently used during clinical finger taps test in patients with Parkinson's disease. A miniature, light-weight gyrosensor free from gravitational artifact was used for measurement of finger taps in order to impose minimal constraint on patients. Forty Parkinson's disease patients and 14 age-matched control subjects participated in the experiments. Subjects' finger taps in both right and left hands were scored by two independent neurologists according to the unified Parkinson's disease rating scale and were also measured by a gyrosensor. Four performance indices were derived from the gyrosensor signal of the index finger. All indices showed significant differences between control and patients (P < 0.001) and also significant correlations with the clinical finger taps score (r = -0.73 to -0.80, P < 0.001). ANOVA showed significant differences in all indices among different finger taps scores (P < 0.001), and post hoc tests showed significant differences in indices between most pairs of non-neighboring and part of neighboring pairs of finger taps scores (P < 0.01). The results suggest that indices from a gyrosensor can be used as quantitative measures of bradykinesia during the finger taps test.

KW - Bradykinesia

KW - Finger taps

KW - Gyrosensor

KW - Parkinson's disease

KW - Quantification

KW - UPDRS

UR - http://www.scopus.com/inward/record.url?scp=79952622008&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952622008&partnerID=8YFLogxK

U2 - 10.1007/s11517-010-0697-8

DO - 10.1007/s11517-010-0697-8

M3 - Article

C2 - 21052856

AN - SCOPUS:79952622008

VL - 49

SP - 365

EP - 371

JO - Medical and Biological Engineering and Computing

JF - Medical and Biological Engineering and Computing

SN - 0140-0118

IS - 3

ER -