Quantification of scattering changes using polarization-sensitive optical coherence tomography

Sang Won Lee, Jin Ho Kang, Ji Yeong Yoo, Moon Sik Kang, Jung Tack Oh, Beop-Min Kim

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We demonstrate that changes in the degree of polarization (DOP) depend on changes in the scattering coefficient, and they can be quantified by using a polarization-sensitive optical coherence tomography (PS-OCT) system. We test our hypothesis using liquid and solid phantoms made from Intralipid suspensions and gelatin, respectively. We also quantify the DOP changes with depth caused by changes in the concentration of scatterers in the liquid and solid phantoms. It is clearly shown that the DOP change has a linear relationship with the scattering change. In our previous study, we showed that the axial slope of the DOP is different between normal and pathologic cervical tissues. Our results demonstrate that the quantification of the axial DOP slope can be used for the systematic diagnosis of Certain tissue pathology.

Original languageEnglish
Article number054032
JournalJournal of Biomedical Optics
Volume13
Issue number5
DOIs
Publication statusPublished - 2008 Sep 15
Externally publishedYes

Fingerprint

Optical tomography
Optical Coherence Tomography
tomography
Scattering
Polarization
polarization
Gelatin
scattering
Suspensions
Pathology
Tissue
slopes
gelatins
scattering coefficients
pathology
Liquids
liquids
phospholipid emulsion soybean oil

Keywords

  • Polarization degree
  • Polarization-sensitive optical coherence tomography
  • Scattering property changes quantification

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Clinical Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering
  • Biomaterials
  • Electronic, Optical and Magnetic Materials

Cite this

Quantification of scattering changes using polarization-sensitive optical coherence tomography. / Lee, Sang Won; Kang, Jin Ho; Yoo, Ji Yeong; Kang, Moon Sik; Oh, Jung Tack; Kim, Beop-Min.

In: Journal of Biomedical Optics, Vol. 13, No. 5, 054032, 15.09.2008.

Research output: Contribution to journalArticle

Lee, Sang Won ; Kang, Jin Ho ; Yoo, Ji Yeong ; Kang, Moon Sik ; Oh, Jung Tack ; Kim, Beop-Min. / Quantification of scattering changes using polarization-sensitive optical coherence tomography. In: Journal of Biomedical Optics. 2008 ; Vol. 13, No. 5.
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