Quantitative Analysis of Calcium Phosphate Nanocluster Growth Using Time-of-Flight Medium-Energy-Ion-Scattering Spectroscopy

Jimin Park, Ki Dong Yang, Na Young Kim, Kang Won Jung, Viet Duc Le, Hee Jin Lim, Junghyun An, Kyoungsuk Jin, Yong Hyun Kim, Ki Tae Nam, Daewon Moon

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

One of the remaining challenges in material chemistry is to unveil the quantitative compositional/structural information and thermodynamic nature of inorganic materials especially in the initial nucleation and growth step. In this report, we adopted newly developed time-of-flight medium-energy-ion-scattering (TOF-MEIS) spectroscopy to address this challenge and explored heterogeneously grown nanometer-sized calcium phosphate as a model system. With TOF-MEIS, we discovered the existence of calcium-rich nanoclusters (Ca/P ∼ 3) in the presence of the non-collagenous-protein-mimicking passivating ligands. Over the reaction, these clusters progressively changed their compositional ratio toward that of a bulk phase (Ca/P ∼ 1.67) with a concurrent increase in their size to ∼2 nm. First-principles studies suggested that the calcium-rich nanoclusters can be stabilized through specific interactions between the ligands and clusters, emphasizing the important role of template on guiding the chemical and thermodynamic nature of inorganic materials at the nanoscale.

Original languageEnglish
Pages (from-to)1253-1260
Number of pages8
JournalACS Central Science
Volume4
Issue number9
DOIs
Publication statusPublished - 2018 Sep 26
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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