Quantitative analysis of methyl parathion pesticides in a polydimethylsiloxane microfluidic channel using confocal surface-enhanced Raman spectroscopy

Donghoon Lee, Sangyeop Lee, Gi Hun Seong, Jaebum Choo, Eun Kyu Lee, Dae Gab Gweon, Sanghoon Lee

Research output: Contribution to journalArticle

115 Citations (Scopus)

Abstract

A fast and ultra-sensitive trace analysis of methyl parathion pesticides in a polydimethylsiloxane (PDMS) microfluidic channel was investigated using confocal surface-enhanced Raman spectroscopy (SERS). A three-dimensional PDMS-based passive micromixer was fabricated for this purpose. This PDMS micromixer showed a high mixing efficiency because a strong chaotic advection was developed by the simultaneous vertical and transverse dispersion of the confluent streams. The confocal SERS signal was measured after methyl parathion pesticides were effectively adsorbed onto silver nanoparticles while flowing along the upper and lower alligator-teeth-shaped PDMS channel. A quantitative analysis of the methyl parathion pesticides was performed based on the measured peak height at 1246 cm-1. Our method has a detection limit of 0.1 ppm. This value satisfies the requirement recommended by the Collaborative International Pesticides Analytical Council (CIPAC) for the determination of methyl parathion in pesticide formulations. This study demonstrates the feasibility of using confocal SERS for the highly sensitive detection of methyl parathion pesticides in a PDMS microfluidic channel.

Original languageEnglish
Pages (from-to)373-377
Number of pages5
JournalApplied Spectroscopy
Volume60
Issue number4
DOIs
Publication statusPublished - 2006 Apr

Keywords

  • Confocal microscopy
  • Microfluidic channel
  • PDMS
  • Pesticide detection
  • Polydimethylsiloxane
  • SERS
  • Surface-enhanced Raman spectroscopy

ASJC Scopus subject areas

  • Instrumentation
  • Spectroscopy

Fingerprint Dive into the research topics of 'Quantitative analysis of methyl parathion pesticides in a polydimethylsiloxane microfluidic channel using confocal surface-enhanced Raman spectroscopy'. Together they form a unique fingerprint.

  • Cite this