Quantitative image analysis of hair follicles in alopecia areata

Kim Il-Hwan, Jo Ho-Yeon, Cho Chang Geun, Hyan Chul Choi, Chil Hwan Oh

    Research output: Contribution to journalArticlepeer-review

    9 Citations (Scopus)


    We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.

    Original languageEnglish
    Pages (from-to)214-216
    Number of pages3
    JournalActa Dermato-Venereologica
    Issue number3
    Publication statusPublished - 1999


    • Alopecia areata
    • Transverse section image analysis

    ASJC Scopus subject areas

    • Dermatology


    Dive into the research topics of 'Quantitative image analysis of hair follicles in alopecia areata'. Together they form a unique fingerprint.

    Cite this