Abstract
We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.
| Original language | English |
|---|---|
| Pages (from-to) | 214-216 |
| Number of pages | 3 |
| Journal | Acta Dermato-Venereologica |
| Volume | 79 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1999 Jun 9 |
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Keywords
- Alopecia areata
- Transverse section image analysis
ASJC Scopus subject areas
- Dermatology
Cite this
Quantitative image analysis of hair follicles in alopecia areata. / Kim, Il-Hwan; Ho-Yeon, Jo; Chang Geun, Cho; Choi, Hyan Chul; Oh, Chil Hwan.
In: Acta Dermato-Venereologica, Vol. 79, No. 3, 09.06.1999, p. 214-216.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Quantitative image analysis of hair follicles in alopecia areata
AU - Kim, Il-Hwan
AU - Ho-Yeon, Jo
AU - Chang Geun, Cho
AU - Choi, Hyan Chul
AU - Oh, Chil Hwan
PY - 1999/6/9
Y1 - 1999/6/9
N2 - We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.
AB - We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.
KW - Alopecia areata
KW - Transverse section image analysis
UR - http://www.scopus.com/inward/record.url?scp=0033048067&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033048067&partnerID=8YFLogxK
U2 - 10.1080/000155599750011002
DO - 10.1080/000155599750011002
M3 - Article
VL - 79
SP - 214
EP - 216
JO - Acta Dermato-Venereologica
JF - Acta Dermato-Venereologica
SN - 0001-5555
IS - 3
ER -