Quantitative image analysis of hair follicles in alopecia areata

Il-Hwan Kim, Jo Ho-Yeon, Cho Chang Geun, Hyan Chul Choi, Chil Hwan Oh

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.

Original languageEnglish
Pages (from-to)214-216
Number of pages3
JournalActa Dermato-Venereologica
Volume79
Issue number3
DOIs
Publication statusPublished - 1999 Jun 9

Fingerprint

Alopecia Areata
Hair Follicle
Alopecia
Hair
Scalp
Biopsy

Keywords

  • Alopecia areata
  • Transverse section image analysis

ASJC Scopus subject areas

  • Dermatology

Cite this

Quantitative image analysis of hair follicles in alopecia areata. / Kim, Il-Hwan; Ho-Yeon, Jo; Chang Geun, Cho; Choi, Hyan Chul; Oh, Chil Hwan.

In: Acta Dermato-Venereologica, Vol. 79, No. 3, 09.06.1999, p. 214-216.

Research output: Contribution to journalArticle

Kim, Il-Hwan ; Ho-Yeon, Jo ; Chang Geun, Cho ; Choi, Hyan Chul ; Oh, Chil Hwan. / Quantitative image analysis of hair follicles in alopecia areata. In: Acta Dermato-Venereologica. 1999 ; Vol. 79, No. 3. pp. 214-216.
@article{4396a88b810b4e68a1801c09e7074c7e,
title = "Quantitative image analysis of hair follicles in alopecia areata",
abstract = "We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.",
keywords = "Alopecia areata, Transverse section image analysis",
author = "Il-Hwan Kim and Jo Ho-Yeon and {Chang Geun}, Cho and Choi, {Hyan Chul} and Oh, {Chil Hwan}",
year = "1999",
month = "6",
day = "9",
doi = "10.1080/000155599750011002",
language = "English",
volume = "79",
pages = "214--216",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato-Venereologica",
number = "3",

}

TY - JOUR

T1 - Quantitative image analysis of hair follicles in alopecia areata

AU - Kim, Il-Hwan

AU - Ho-Yeon, Jo

AU - Chang Geun, Cho

AU - Choi, Hyan Chul

AU - Oh, Chil Hwan

PY - 1999/6/9

Y1 - 1999/6/9

N2 - We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.

AB - We took biopsies from similar sites on the scalps of normal controls, normal looking and hair loss areas of patients with alopecia areata. The specimens were sectioned serially and horizontally. We measured morphological parameters, such as the diameter of the hair shaft, the thickness of the inner root sheath, the diameter of the outer root sheath, the irregularity of the outer root sheath and the ratio between the diameters of the hair shaft and the outer root sheath, using a computerized image analysis system. There were significant differences in 5 parameters between hair loss areas and normal controls. The proportions of vellus and telogen hair were significantly higher in the areata areas than in the controls. The 5 morphological parameters and most quantitative-measured parameters of normal- looking areas from patients with alopecia values intermediate between the other groups.

KW - Alopecia areata

KW - Transverse section image analysis

UR - http://www.scopus.com/inward/record.url?scp=0033048067&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033048067&partnerID=8YFLogxK

U2 - 10.1080/000155599750011002

DO - 10.1080/000155599750011002

M3 - Article

VL - 79

SP - 214

EP - 216

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

IS - 3

ER -