Quantitative trait loci mapping for fatty acid contents in the backfat on porcine chromosomes 1, 13, and 18

Chaeyoung Lee, Yeonseung Chung, Jae-Hong Kim

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A partial genome scan using microsatellite markers was conducted in order to detect quantitative trait loci (QTLs) for 10 fatty acid contents of the backfat in a pig reference population. Two QTLs were found by studying SSC1, SSC13, and SSC18, where QTLs had already been identified for backfat thickness. A QTL was located between marker loci S0113 and SW974 on chromosome 1; this QTL was only significantly detected (P < 0.05) for Iinoleic acid. The other QTL was discovered between markers S0062 and S0120 on chromosome 18, and its significance only showed (P < 0.05) for myristic acid. The two QTLs mapped to the same location as the backfat thickness QTL. A third of the phenotypic variation was explained for Iinoleic acid by the QTL on chromosome 1, and a quarter for myristic acid by the QTL on chromosome 18. Further studies on fine mapping and positional comparative candidate gene analyses will be the next step toward a better understanding of the genetic architecture of fatty acid contents.

Original languageEnglish
Pages (from-to)62-67
Number of pages6
JournalMolecules and Cells
Volume15
Issue number1
Publication statusPublished - 2003 Feb 1

Fingerprint

Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 1
Quantitative Trait Loci
Swine
Fatty Acids
Myristic Acid
Acids
Genetic Association Studies
Microsatellite Repeats
Genome

Keywords

  • Fatty Acids
  • Genome Scan
  • Microsatellites
  • Quantitative Traits

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cell Biology

Cite this

Quantitative trait loci mapping for fatty acid contents in the backfat on porcine chromosomes 1, 13, and 18. / Lee, Chaeyoung; Chung, Yeonseung; Kim, Jae-Hong.

In: Molecules and Cells, Vol. 15, No. 1, 01.02.2003, p. 62-67.

Research output: Contribution to journalArticle

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