Radiation exposure and cancer mortality among nuclear power plant workers: A meta-analysis

Eun Sook Park, Kieun Moon, Han Na Kim, Won Jin Lee, Young Woo Jin

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objectives: We conducted a meta-analysis to investigate the relationship between low external doses of ionizing radiation exposure and the risk of cancer mortality among nuclear power plant workers. Methods: We searched MEDLINE using key words related to low dose and cancer risk. The selected articles were restricted to those written in English from 1990 to January 2009. We excluded those studies with no fit to the selection criteria and we included the cited references in published articles to minimize publication bias. Through this process, a total of 11 epidemiologic studies were finally included. A publication bias was tested for using Egger's test. The homogeneity test was performed before the integration of each of the standardized mortality ratios (SMRs) and the result proved that the studies were heterogeneous. Results: We found significant decreased deaths from all cancers (SMR = 0.75, 95% CI = 0.62 - 0.90), all cancers excluding leukemia, solid cancer, mouth and pharynx, esophagus, stomach, rectum, liver and gallbladder, pancreas, lung, prostate, lymphopoietic and hematopoitic cancer. The findings of this meta-analysis were similar with those of the 15 Country Collaborative Study conducted by the International Agency for Research on Cancer. A publication bias was found only for liver and gallbladder cancer (p = 0.015). Heterogeneity was observed for all cancers, all cancers excluding leukemia, solid cancer, esophagus, colon and lung cancer. Conclusions: Our findings of low mortality for stomach, rectum, liver and gallbladder cancers may explained by the health worker effect Yet further studies are needed to clarify the low SMR of cancers, for which there is no useful screening tool, in nuclear power plant workers.

Original languageEnglish
Pages (from-to)185-192
Number of pages8
JournalJournal of Preventive Medicine and Public Health
Volume43
Issue number2
DOIs
Publication statusPublished - 2010 Mar 1

Fingerprint

Nuclear Power Plants
Meta-Analysis
Mortality
Publication Bias
Neoplasms
Gallbladder Neoplasms
Liver Neoplasms
Esophageal Neoplasms
Colonic Neoplasms
Lung Neoplasms
Leukemia
Pharyngeal Neoplasms
International Agencies
Radiation Exposure
Mouth Neoplasms
Rectal Neoplasms
Ionizing Radiation
Gallbladder
Rectum
MEDLINE

Keywords

  • Cancer
  • Meta-analysis
  • Radiation worker
  • Standardized mortality ratio

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Radiation exposure and cancer mortality among nuclear power plant workers : A meta-analysis. / Park, Eun Sook; Moon, Kieun; Kim, Han Na; Lee, Won Jin; Jin, Young Woo.

In: Journal of Preventive Medicine and Public Health, Vol. 43, No. 2, 01.03.2010, p. 185-192.

Research output: Contribution to journalArticle

Park, Eun Sook ; Moon, Kieun ; Kim, Han Na ; Lee, Won Jin ; Jin, Young Woo. / Radiation exposure and cancer mortality among nuclear power plant workers : A meta-analysis. In: Journal of Preventive Medicine and Public Health. 2010 ; Vol. 43, No. 2. pp. 185-192.
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