Radical cyclization of β-aminoacrylates: Synthesis of (-)-indolizidine 223AB

Eun Lee, Eun Jeong Jeong, Sun Joon Min, Sukwon Hong, Jaehong Lim, Sang Kyun Kim, Hak Joong Kim, Bum Gyu Choi, Ki Chul Koo

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32 Citations (Scopus)


matrix presented (-)-Indolizidine 223AB was synthesized via radical cyclization of the β-aminoacrylate derivative of a trans-2,5-disubstituted pyrrolidine. The trans-2,5-disubstituted pyrrolidine substrate was prepared by radical cyclization of a Ses-protected β-aminoacrylate.

Original languageEnglish
Pages (from-to)2169-2171
Number of pages3
JournalOrganic Letters
Issue number14
Publication statusPublished - 2000 Jul 13
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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    Lee, E., Jeong, E. J., Min, S. J., Hong, S., Lim, J., Kim, S. K., Kim, H. J., Choi, B. G., & Koo, K. C. (2000). Radical cyclization of β-aminoacrylates: Synthesis of (-)-indolizidine 223AB. Organic Letters, 2(14), 2169-2171. https://doi.org/10.1021/ol006094z