Radiographic and histologic characterization of tongue base tissues obtained by transoral robotic surgery in patients with obstructive sleep apnea

Jeong Whun Kim, Seung Hoon Lee, Hong Joong Kim, Chae Seo Rhee, Seung No Hong

Research output: Contribution to journalArticle

Abstract

Objective: Our aim was to radiographically and histologically characterize the tongue base tissues removed after robotic surgery and to analyze their relationship with polysomnographic measurements in obstructive sleep apnea. Methods: Medical records, radiographs and histologic specimen of the patients who underwent transoral robotic tongue base reduction surgery were retrospectively reviewed. Findings in computed tomography (CT) images, histopathological features of the removed tongue base tissues, and respiratory parameters in polysomnography were compared and analyzed. Results: Surgical specimens and CT images were available from 13 patients (aged 29–61 years). Histologic examination showed that the removed tissues comprised four layers—epithelial, lymphoid follicular, glandular, and muscle tissue. The median (interquartile range) thickness of the epithelial, lymphoid, and glandular layers was 0.29 (0.24–0.44) mm, 3.37 (1.67–4.75) mm, and 3.75 (3.45–4.10) mm, respectively. The lymphoid layer thickness on CT was correlated with that in the histologic section (r = 0.967, p < 0.001). However, the thickness of each layer had no significant correlation with the polysomnographic parameters. Conclusion: The tongue base tissue removed by transoral robotic surgery in OSA patients comprised four distinctive layers including epithelial, lymphoid follicular, glandular and muscular layers. These layered structures could also be discriminated in the CT images.

Original languageEnglish
Pages (from-to)89-94
Number of pages6
JournalAuris Nasus Larynx
Volume46
Issue number1
DOIs
Publication statusPublished - 2019 Feb 1

Keywords

  • Histology
  • Obstructive sleep apnea
  • Robotic surgical procedure
  • Tongue base

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

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