Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid

Tuhin Pradhan, Sukhendu Maiti, Rajesh Kumar, Yun Hak Lee, Jong Wan Kim, Joung Hae Lee, Jong Seung Kim

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Abstract The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: ∼60 μM, higher: ∼700 μM and normal: ∼120-380 μM) with 'turn-on' fluorogenic behaviour.

Original languageEnglish
Article number4764
Pages (from-to)1-6
Number of pages6
JournalDyes and Pigments
Volume121
DOIs
Publication statusPublished - 2015 May 26

Keywords

  • BODIPY
  • Fluorescence
  • Hydrogen bonding
  • Non-enzymatic
  • PET
  • Uric acid

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Process Chemistry and Technology

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  • Cite this

    Pradhan, T., Maiti, S., Kumar, R., Lee, Y. H., Kim, J. W., Lee, J. H., & Kim, J. S. (2015). Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid. Dyes and Pigments, 121, 1-6. [4764]. https://doi.org/10.1016/j.dyepig.2015.05.001