Abstract
Abstract The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: ∼60 μM, higher: ∼700 μM and normal: ∼120-380 μM) with 'turn-on' fluorogenic behaviour.
| Original language | English |
|---|---|
| Article number | 4764 |
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| Journal | Dyes and Pigments |
| Volume | 121 |
| DOIs | |
| Publication status | Published - 2015 May 26 |
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Keywords
- BODIPY
- Fluorescence
- Hydrogen bonding
- Non-enzymatic
- PET
- Uric acid
ASJC Scopus subject areas
- Chemical Engineering(all)
- Process Chemistry and Technology
Cite this
Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid. / Pradhan, Tuhin; Maiti, Sukhendu; Kumar, Rajesh; Lee, Yun Hak; Kim, Jong Wan; Lee, Joung Hae; Kim, Jong Seung.
In: Dyes and Pigments, Vol. 121, 4764, 26.05.2015, p. 1-6.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rationally designed non-enzymatic fluorogenic 'turn-on' probe for uric acid
AU - Pradhan, Tuhin
AU - Maiti, Sukhendu
AU - Kumar, Rajesh
AU - Lee, Yun Hak
AU - Kim, Jong Wan
AU - Lee, Joung Hae
AU - Kim, Jong Seung
PY - 2015/5/26
Y1 - 2015/5/26
N2 - Abstract The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: ∼60 μM, higher: ∼700 μM and normal: ∼120-380 μM) with 'turn-on' fluorogenic behaviour.
AB - Abstract The simple and cost-effective detection of uric acid in serum or urine is highly desirable as uric acid acts as a biomarker for various diseases. Herein, we report a rationally designed, non-enzymatic probe for the detection of uric acid in serum samples over a wide range of concentrations (lower: ∼60 μM, higher: ∼700 μM and normal: ∼120-380 μM) with 'turn-on' fluorogenic behaviour.
KW - BODIPY
KW - Fluorescence
KW - Hydrogen bonding
KW - Non-enzymatic
KW - PET
KW - Uric acid
UR - http://www.scopus.com/inward/record.url?scp=84929991029&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929991029&partnerID=8YFLogxK
U2 - 10.1016/j.dyepig.2015.05.001
DO - 10.1016/j.dyepig.2015.05.001
M3 - Article
VL - 121
SP - 1
EP - 6
JO - Dyes and Pigments
JF - Dyes and Pigments
SN - 0143-7208
M1 - 4764
ER -