Real-time detection of trace copper in brain and kidney of fish for medical diagnosis

Young Kyun Yang, Eun Chul Pack, Seung Ha Lee, Hai Soo Yoo, DalWoong Choi, Suw Young Ly

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

For the detection of trace copper to be used in medical diagnosis, a sensitive handmade carbon nanotube paste electrode (PE) was developed using voltammetry. Analytical optimized conditions were found at 0.05 V anodic peak current. In the same conditions, various common electrodes were compared using stripping voltammetry, and the PE was found to be more sharply sensitive than other common electrodes. At optimum conditions, the working ranges of 3~19 μgL-1 were obtained. The relative standard deviation of 70.0 μgL-1 was determined to be 0.117% (n = 15), and the detection limit (S/N) was found to be 0.6 μgL-1 (9.4 × 10-9 M). The results were applied in detecting copper traces in the kidney and the brain cells of fish.

Original languageEnglish
Pages (from-to)311-316
Number of pages6
JournalToxicological Research
Volume30
Issue number4
DOIs
Publication statusPublished - 2014

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Keywords

  • Brain cells
  • Copper
  • Fish
  • Kidney
  • Paste electrode

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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