TY - JOUR
T1 - Real-time fMRI-based neurofeedback reinforces causality of attention networks
AU - Lee, Jong Hwan
AU - Kim, Junghoe
AU - Yoo, Seung Schik
N1 - Funding Information:
This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.
PY - 2012/4
Y1 - 2012/4
N2 - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.
AB - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.
KW - Auditory attention
KW - Effective connectivity
KW - Functional MRI (fMRI)
KW - Granger causality
KW - Neurofeedback
KW - Real-time fMRI
UR - http://www.scopus.com/inward/record.url?scp=84862779855&partnerID=8YFLogxK
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U2 - 10.1016/j.neures.2012.01.002
DO - 10.1016/j.neures.2012.01.002
M3 - Article
C2 - 22285603
AN - SCOPUS:84862779855
VL - 72
SP - 347
EP - 354
JO - Neuroscience Research
JF - Neuroscience Research
SN - 0168-0102
IS - 4
ER -