Real-time fMRI-based neurofeedback reinforces causality of attention networks

Jong Hwan Lee; Junghoe Kim; Seung Schik Yoo

doi:10.1016/j.neures.2012.01.002

Real-time fMRI-based neurofeedback reinforces causality of attention networks

Jong Hwan Lee, Junghoe Kim, Seung Schik Yoo

Department of Brain and Cognitive Engineering

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

Original language	English
Pages (from-to)	347-354
Number of pages	8
Journal	Neuroscience Research
Volume	72
Issue number	4
DOIs	https://doi.org/10.1016/j.neures.2012.01.002
Publication status	Published - 2012 Apr

Keywords

Auditory attention
Effective connectivity
Functional MRI (fMRI)
Granger causality
Neurofeedback
Real-time fMRI

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/j.neures.2012.01.002

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title = "Real-time fMRI-based neurofeedback reinforces causality of attention networks",

abstract = "In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received {"} sham{"} feedback. This {"} dynamic{"} characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.",

keywords = "Auditory attention, Effective connectivity, Functional MRI (fMRI), Granger causality, Neurofeedback, Real-time fMRI",

author = "Lee, {Jong Hwan} and Junghoe Kim and Yoo, {Seung Schik}",

note = "Funding Information: This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.",

year = "2012",

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doi = "10.1016/j.neures.2012.01.002",

language = "English",

volume = "72",

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journal = "Neuroscience Research",

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AU - Lee, Jong Hwan

AU - Kim, Junghoe

AU - Yoo, Seung Schik

N1 - Funding Information: This work was supported by the World Class University (WCU) program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education, Science and Technology ( R31-10008 ) and the Basic Science Research Program , NRF grant of Korea ( 2011-0004794 ). These sponsors had no involvement in study design, data collection, analysis or interpretation of data, manuscript preparation, or the decision to submit for publication.

PY - 2012/4

Y1 - 2012/4

N2 - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

AB - In this study, we investigated the efficacy of a real-time functional magnetic resonance imaging (rtfMRI)-based neurofeedback method for the modulation of the effective connectivity (EC) of causality between attention-related neuronal activities. In participants who received the feedback of attention-related neuronal activity, the EC estimated from Granger causality analysis was reinforced within the task-related network, such as between the bilateral cingulate gyri and frontal cortices, whereas the EC between the task-related network and task-unrelated resting-state network, including the inferior parietal lobule, was diminished. On the other hand, only marginal changes were observed in participants who received " sham" feedback. This " dynamic" characteristic measure of EC based on causality may be useful for evaluating the efficacy of methods designed to modulate brain networks, including rtfMRI-based neurofeedback.

KW - Auditory attention

KW - Effective connectivity

KW - Functional MRI (fMRI)

KW - Granger causality

KW - Neurofeedback

KW - Real-time fMRI

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JO - Neuroscience Research

JF - Neuroscience Research

SN - 0168-0102

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ER -

Real-time fMRI-based neurofeedback reinforces causality of attention networks

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Keywords

ASJC Scopus subject areas

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