Recent advances in anticancer chemotherapeutics based upon azepine scaffold

Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong Shin Chang, Kyeong Lee, Yongseok Choi

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Original languageEnglish
Pages (from-to)539-557
Number of pages19
JournalAnti-Cancer Agents in Medicinal Chemistry
Volume16
Issue number5
Publication statusPublished - 2016 May 1

Keywords

  • Anticancer agents
  • Azepane scaffold
  • Chemotherapeutics
  • Histone deacetylases
  • Hormone modulators
  • Kinase inhibitors
  • Phototherapeutic agents
  • Tubulin inhibitors

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Medicine
  • Pharmacology

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  • Cite this

    Singh, S., Goo, J., Gajulapati, V., Chang, T. S., Lee, K., & Choi, Y. (2016). Recent advances in anticancer chemotherapeutics based upon azepine scaffold. Anti-Cancer Agents in Medicinal Chemistry, 16(5), 539-557.