Recent advances in anticancer chemotherapeutics based upon azepine scaffold

Sarbjit Singh, Jail Goo, Veeraswamy Gajulapati, Tong Shin Chang, Kyeong Lee, Yongseok Choi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.

Original languageEnglish
Pages (from-to)539-557
Number of pages19
JournalAnti-Cancer Agents in Medicinal Chemistry
Volume16
Issue number5
Publication statusPublished - 2016 May 1

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Azepines
Neoplasms

Keywords

  • Anticancer agents
  • Azepane scaffold
  • Chemotherapeutics
  • Histone deacetylases
  • Hormone modulators
  • Kinase inhibitors
  • Phototherapeutic agents
  • Tubulin inhibitors

ASJC Scopus subject areas

  • Cancer Research
  • Molecular Medicine
  • Pharmacology

Cite this

Singh, S., Goo, J., Gajulapati, V., Chang, T. S., Lee, K., & Choi, Y. (2016). Recent advances in anticancer chemotherapeutics based upon azepine scaffold. Anti-Cancer Agents in Medicinal Chemistry, 16(5), 539-557.

Recent advances in anticancer chemotherapeutics based upon azepine scaffold. / Singh, Sarbjit; Goo, Jail; Gajulapati, Veeraswamy; Chang, Tong Shin; Lee, Kyeong; Choi, Yongseok.

In: Anti-Cancer Agents in Medicinal Chemistry, Vol. 16, No. 5, 01.05.2016, p. 539-557.

Research output: Contribution to journalArticle

Singh, S, Goo, J, Gajulapati, V, Chang, TS, Lee, K & Choi, Y 2016, 'Recent advances in anticancer chemotherapeutics based upon azepine scaffold', Anti-Cancer Agents in Medicinal Chemistry, vol. 16, no. 5, pp. 539-557.
Singh, Sarbjit ; Goo, Jail ; Gajulapati, Veeraswamy ; Chang, Tong Shin ; Lee, Kyeong ; Choi, Yongseok. / Recent advances in anticancer chemotherapeutics based upon azepine scaffold. In: Anti-Cancer Agents in Medicinal Chemistry. 2016 ; Vol. 16, No. 5. pp. 539-557.
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