Recent advances in statistics

Almost all clinical researchers have had at least one experience of receiving a request for statistical correction after submitting a manuscript to a scientific journal. Some of these requests may have been about matters that were not previously considered problematic, such as the application of unfamiliar statistical techniques, consideration of study details, or presentation of newer, better alternatives beyond P values. Many researchers may be embarrassed by these unexpected requests. Statistical science is changing rapidly with advances in computer technology and statistical software. In many cases, statistical methods accepted 20 years ago are now considered outdated or unacceptable.