TY - JOUR
T1 - Recent developments in nanoformulations of lipophilic functional foods
AU - Shin, Gye Hwa
AU - Kim, Jun Tae
AU - Park, Hyun Jin
N1 - Funding Information:
This research was supported by the International Research & Development Program of the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (MEST) of Korea (Grant number: NRF-2012K1A3A1A20031356 ).
PY - 2015/1/15
Y1 - 2015/1/15
N2 - Recently, nutraceuticals have great attention due to their excellent functional properties for health promotion and disease prevention. Especially, lipophilic materials could give various health benefits such as antioxidant, anti-inflammatory, wound healing, and even anti-cancer effects. However, there are some limitations to apply them into food system and oral administration due to their poor water solubility, low oral absorption, and poor bioavailability which are pivotal issues to overcome for lipophilic nutraceuticals. In this review, various nanoformulations have been introduced with their advantages and disadvantages, including those that can enhance solubility and bioavailability of bioactive compounds.
AB - Recently, nutraceuticals have great attention due to their excellent functional properties for health promotion and disease prevention. Especially, lipophilic materials could give various health benefits such as antioxidant, anti-inflammatory, wound healing, and even anti-cancer effects. However, there are some limitations to apply them into food system and oral administration due to their poor water solubility, low oral absorption, and poor bioavailability which are pivotal issues to overcome for lipophilic nutraceuticals. In this review, various nanoformulations have been introduced with their advantages and disadvantages, including those that can enhance solubility and bioavailability of bioactive compounds.
KW - Functional foods
KW - Inclusion complex
KW - Nano-carrier system
KW - Nanoemulsions
KW - Nanoliposomes
KW - Nanostructured lipid carriers
KW - Nanosuspensions
KW - Nutraceuticals
KW - Polymeric nanoparticles
KW - Protein-based carriers
KW - Self-emulsifying drug delivery systems
KW - Solid lipid nanoparticles
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U2 - 10.1016/j.tifs.2015.07.005
DO - 10.1016/j.tifs.2015.07.005
M3 - Article
AN - SCOPUS:84955669486
VL - 46
SP - 144
EP - 157
JO - Trends in Food Science and Technology
JF - Trends in Food Science and Technology
SN - 0924-2244
IS - 1
ER -