Recent review on blood transfusion therapy

Research output: Contribution to journalReview article

Abstract

Blood transfusion is an essential part of medical care, but it has risks, including infectious and immunologic complications. Recent medical practice emphasizes the rationalization of transfusion according to guidelines at the national and local levels. Early transfusions used whole blood, but modern practice commonly uses only components of the blood, such as red blood cells, platelets, plasma, and clotting factors. Red blood cell transfusions are indicated to improve oxygen delivery to tissues and to treat hemorrhage. Platelet transfusion may be indicated to prevent hemorrhage in patients with thrombocytopenia or functionally abnormal platelets. Fresh frozen plasma can be used to correct coagulation abnormalities in order to normalize the fibrinogen level, prothrombin time, and activated partial thromboplastin time. Cryoprecipitate is indicated for bleeding associated with fibrinogen deficiencies, factor XIII deficiency, hemophilia A, or von Willebrand's disease. However, blood transfusion should be based on guidelines as well as the patient's clinical condition. Appropriate use of blood components results in effective transfusion therapy and reduces transfusion-related complications.

Original languageEnglish
Pages (from-to)496-503
Number of pages8
JournalJournal of the Korean Medical Association
Volume56
Issue number6
DOIs
Publication statusPublished - 2013 Jun 1

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Blood Transfusion
Hemorrhage
Factor XIII Deficiency
Blood Platelets
Afibrinogenemia
Guidelines
von Willebrand Diseases
Erythrocyte Transfusion
Platelet Transfusion
Blood Coagulation Factors
Partial Thromboplastin Time
Prothrombin Time
Hemophilia A
Thrombocytopenia
Fibrinogen
Therapeutics
Erythrocytes
Oxygen

Keywords

  • Blood transfusion
  • Guideline

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Recent review on blood transfusion therapy. / Kim, Jae Hwan.

In: Journal of the Korean Medical Association, Vol. 56, No. 6, 01.06.2013, p. 496-503.

Research output: Contribution to journalReview article

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