Recent trends in pharmacologic treatment of cancer pain

Keun Sook Sohn, Jae Hwan Kim

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Cancer pain is among the most undesirable side effects and complications for cancer patients. Severe cancer pain acts as physical and psychological stress and makes it difficult for patients to perform daily activities. Uncontrolled cancer pain can be emotionally devastating to patients. However, cancer pain can be controlled with pharmacologic treatment. Traditionally, cancer pain was treated according to the WHO three-step analgesic ladder based on the severity of pain. Recently, it has become to administer weak opioids as well as non-opioid analgesics to patients with mild pain. For moderate pain, weak opioids or strong opioids can be used. Non-opioid analgesics and adjuvant analgesics can be used as an adjuvant to opioids for all severities of cancer pain. Effective cancer pain management depends on the proper selection of a drug, dose, and route and depends on treatment of common side effects associated with the medication. The usage of medication should be individualized to each patient. If necessary, we may use other modalities such as radiotherapy, nerve block, and non-pharmacologic interventions for cancer pain control. The goal of treatment of cancer pain is to obtain complete or partial pain relief with tolerable side effects of the medication, and ultimately, to improve the quality of life of cancer patients.

Original languageEnglish
Pages (from-to)666-675
Number of pages10
JournalJournal of the Korean Medical Association
Volume55
Issue number7
DOIs
Publication statusPublished - 2012 Jul 1

Fingerprint

Opioid Analgesics
Analgesics
Pain
Therapeutics
Cancer Pain
Nerve Block
Pain Management
Psychological Stress
Neoplasms
Radiotherapy
Quality of Life
Pharmaceutical Preparations

Keywords

  • Drug therapy
  • Neoplasms
  • Pain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Recent trends in pharmacologic treatment of cancer pain. / Sohn, Keun Sook; Kim, Jae Hwan.

In: Journal of the Korean Medical Association, Vol. 55, No. 7, 01.07.2012, p. 666-675.

Research output: Contribution to journalReview article

@article{f26984cf869a431cb4c43a7a745440c2,
title = "Recent trends in pharmacologic treatment of cancer pain",
abstract = "Cancer pain is among the most undesirable side effects and complications for cancer patients. Severe cancer pain acts as physical and psychological stress and makes it difficult for patients to perform daily activities. Uncontrolled cancer pain can be emotionally devastating to patients. However, cancer pain can be controlled with pharmacologic treatment. Traditionally, cancer pain was treated according to the WHO three-step analgesic ladder based on the severity of pain. Recently, it has become to administer weak opioids as well as non-opioid analgesics to patients with mild pain. For moderate pain, weak opioids or strong opioids can be used. Non-opioid analgesics and adjuvant analgesics can be used as an adjuvant to opioids for all severities of cancer pain. Effective cancer pain management depends on the proper selection of a drug, dose, and route and depends on treatment of common side effects associated with the medication. The usage of medication should be individualized to each patient. If necessary, we may use other modalities such as radiotherapy, nerve block, and non-pharmacologic interventions for cancer pain control. The goal of treatment of cancer pain is to obtain complete or partial pain relief with tolerable side effects of the medication, and ultimately, to improve the quality of life of cancer patients.",
keywords = "Drug therapy, Neoplasms, Pain",
author = "Sohn, {Keun Sook} and Kim, {Jae Hwan}",
year = "2012",
month = "7",
day = "1",
doi = "10.5124/jkma.2012.55.7.666",
language = "English",
volume = "55",
pages = "666--675",
journal = "Journal of the Korean Medical Association",
issn = "1975-8456",
publisher = "Korean Medical Association",
number = "7",

}

TY - JOUR

T1 - Recent trends in pharmacologic treatment of cancer pain

AU - Sohn, Keun Sook

AU - Kim, Jae Hwan

PY - 2012/7/1

Y1 - 2012/7/1

N2 - Cancer pain is among the most undesirable side effects and complications for cancer patients. Severe cancer pain acts as physical and psychological stress and makes it difficult for patients to perform daily activities. Uncontrolled cancer pain can be emotionally devastating to patients. However, cancer pain can be controlled with pharmacologic treatment. Traditionally, cancer pain was treated according to the WHO three-step analgesic ladder based on the severity of pain. Recently, it has become to administer weak opioids as well as non-opioid analgesics to patients with mild pain. For moderate pain, weak opioids or strong opioids can be used. Non-opioid analgesics and adjuvant analgesics can be used as an adjuvant to opioids for all severities of cancer pain. Effective cancer pain management depends on the proper selection of a drug, dose, and route and depends on treatment of common side effects associated with the medication. The usage of medication should be individualized to each patient. If necessary, we may use other modalities such as radiotherapy, nerve block, and non-pharmacologic interventions for cancer pain control. The goal of treatment of cancer pain is to obtain complete or partial pain relief with tolerable side effects of the medication, and ultimately, to improve the quality of life of cancer patients.

AB - Cancer pain is among the most undesirable side effects and complications for cancer patients. Severe cancer pain acts as physical and psychological stress and makes it difficult for patients to perform daily activities. Uncontrolled cancer pain can be emotionally devastating to patients. However, cancer pain can be controlled with pharmacologic treatment. Traditionally, cancer pain was treated according to the WHO three-step analgesic ladder based on the severity of pain. Recently, it has become to administer weak opioids as well as non-opioid analgesics to patients with mild pain. For moderate pain, weak opioids or strong opioids can be used. Non-opioid analgesics and adjuvant analgesics can be used as an adjuvant to opioids for all severities of cancer pain. Effective cancer pain management depends on the proper selection of a drug, dose, and route and depends on treatment of common side effects associated with the medication. The usage of medication should be individualized to each patient. If necessary, we may use other modalities such as radiotherapy, nerve block, and non-pharmacologic interventions for cancer pain control. The goal of treatment of cancer pain is to obtain complete or partial pain relief with tolerable side effects of the medication, and ultimately, to improve the quality of life of cancer patients.

KW - Drug therapy

KW - Neoplasms

KW - Pain

UR - http://www.scopus.com/inward/record.url?scp=84864035530&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84864035530&partnerID=8YFLogxK

U2 - 10.5124/jkma.2012.55.7.666

DO - 10.5124/jkma.2012.55.7.666

M3 - Review article

VL - 55

SP - 666

EP - 675

JO - Journal of the Korean Medical Association

JF - Journal of the Korean Medical Association

SN - 1975-8456

IS - 7

ER -