Reduced striatal dopamine D2 receptors in people with Internet addiction

Sang Hee Kim, Sang Hyun Baik, Chang Soo Park, Su Jin Kim, Sung Won Choi, Sang Eun Kim

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

An increasing amount of research has suggested that Internet addiction is associated with abnormalities in the dopaminergic brain system. We hypothesized that Internet addiction would be associated with reduced levels of dopaminergic receptor availability in the striatum compared with controls. To test this hypothesis, a radiolabeled ligand [11C]raclopride and positron emission tomography was used to assess dopamine D2 receptor binding potential in men with and without Internet addiction. Consistent with our prediction, individuals with Internet addiction showed reduced levels of dopamine D2 receptor availability in subdivisions of the striatum including the bilateral dorsal caudate and right putamen. This finding contributes to the understanding of neurobiological mechanism of Internet addiction.

Original languageEnglish
Pages (from-to)407-411
Number of pages5
JournalNeuroreport
Volume22
Issue number8
DOIs
Publication statusPublished - 2011 Jun 11

Keywords

  • Caudate
  • PET
  • [C]raclopride
  • dopamine D2 receptor
  • internet addiction
  • putamen
  • striatum

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Reduced striatal dopamine D2 receptors in people with Internet addiction'. Together they form a unique fingerprint.

  • Cite this

    Kim, S. H., Baik, S. H., Park, C. S., Kim, S. J., Choi, S. W., & Kim, S. E. (2011). Reduced striatal dopamine D2 receptors in people with Internet addiction. Neuroreport, 22(8), 407-411. https://doi.org/10.1097/WNR.0b013e328346e16e