Reflex vocal fold adduction in the porcine model

The effects of stimuli delivered to various sensory nerves

Jeong-Soo Woo, Jagdeep S. Hundal, Clarence T. Sasaki, Mikhail W. Abdelmessih, Stephen P. Kelleher

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objectives: The aim of this study was to identify a panel of sensory nerves capable of eliciting an evoked glottic closure reflex (GCR) and to quantify the glottic closing force (GCF) of these responses in a porcine model. Methods: In 5 pigs, the internal branch of the superior laryngeal nerve (iSLN) and the trigeminal, pharyngeal plexus, glossopharyngeal, radial, and intercostal nerves were surgically isolated and electrically stimulated. During stimulation of each nerve, the GCR was detected by laryngeal electromyography and the GCF was measured with a pressure transducer. Results: The only nerve that elicited the GCR in the 5 pigs was the iSLN. The average GCF was 288.9 mm Hg. Conclusions: This study demonstrates that the only afferent nerve that elicits the GCR in pigs is the iSLN, and that it should remain the focus of research for the rehabilitation of patients with absent or defective reflex vocal fold adduction.

Original languageEnglish
Pages (from-to)749-752
Number of pages4
JournalAnnals of Otology, Rhinology and Laryngology
Volume117
Issue number10
DOIs
Publication statusPublished - 2008 Jan 1
Externally publishedYes

Fingerprint

Vocal Cords
Tongue
Reflex
Swine
Laryngeal Nerves
Intercostal Nerves
Glossopharyngeal Nerve
Pressure Transducers
Radial Nerve
Electromyography

Keywords

  • Afferent nerve
  • Electrical stimulation
  • Glottis
  • Neuron
  • Reflex

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Reflex vocal fold adduction in the porcine model : The effects of stimuli delivered to various sensory nerves. / Woo, Jeong-Soo; Hundal, Jagdeep S.; Sasaki, Clarence T.; Abdelmessih, Mikhail W.; Kelleher, Stephen P.

In: Annals of Otology, Rhinology and Laryngology, Vol. 117, No. 10, 01.01.2008, p. 749-752.

Research output: Contribution to journalArticle

Woo, Jeong-Soo ; Hundal, Jagdeep S. ; Sasaki, Clarence T. ; Abdelmessih, Mikhail W. ; Kelleher, Stephen P. / Reflex vocal fold adduction in the porcine model : The effects of stimuli delivered to various sensory nerves. In: Annals of Otology, Rhinology and Laryngology. 2008 ; Vol. 117, No. 10. pp. 749-752.
@article{f1cc4e39d9b442c694e6289f239389e0,
title = "Reflex vocal fold adduction in the porcine model: The effects of stimuli delivered to various sensory nerves",
abstract = "Objectives: The aim of this study was to identify a panel of sensory nerves capable of eliciting an evoked glottic closure reflex (GCR) and to quantify the glottic closing force (GCF) of these responses in a porcine model. Methods: In 5 pigs, the internal branch of the superior laryngeal nerve (iSLN) and the trigeminal, pharyngeal plexus, glossopharyngeal, radial, and intercostal nerves were surgically isolated and electrically stimulated. During stimulation of each nerve, the GCR was detected by laryngeal electromyography and the GCF was measured with a pressure transducer. Results: The only nerve that elicited the GCR in the 5 pigs was the iSLN. The average GCF was 288.9 mm Hg. Conclusions: This study demonstrates that the only afferent nerve that elicits the GCR in pigs is the iSLN, and that it should remain the focus of research for the rehabilitation of patients with absent or defective reflex vocal fold adduction.",
keywords = "Afferent nerve, Electrical stimulation, Glottis, Neuron, Reflex",
author = "Jeong-Soo Woo and Hundal, {Jagdeep S.} and Sasaki, {Clarence T.} and Abdelmessih, {Mikhail W.} and Kelleher, {Stephen P.}",
year = "2008",
month = "1",
day = "1",
doi = "10.1177/000348940811701008",
language = "English",
volume = "117",
pages = "749--752",
journal = "Annals of Otology, Rhinology and Laryngology",
issn = "0003-4894",
publisher = "Annals Publishing Company",
number = "10",

}

TY - JOUR

T1 - Reflex vocal fold adduction in the porcine model

T2 - The effects of stimuli delivered to various sensory nerves

AU - Woo, Jeong-Soo

AU - Hundal, Jagdeep S.

AU - Sasaki, Clarence T.

AU - Abdelmessih, Mikhail W.

AU - Kelleher, Stephen P.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Objectives: The aim of this study was to identify a panel of sensory nerves capable of eliciting an evoked glottic closure reflex (GCR) and to quantify the glottic closing force (GCF) of these responses in a porcine model. Methods: In 5 pigs, the internal branch of the superior laryngeal nerve (iSLN) and the trigeminal, pharyngeal plexus, glossopharyngeal, radial, and intercostal nerves were surgically isolated and electrically stimulated. During stimulation of each nerve, the GCR was detected by laryngeal electromyography and the GCF was measured with a pressure transducer. Results: The only nerve that elicited the GCR in the 5 pigs was the iSLN. The average GCF was 288.9 mm Hg. Conclusions: This study demonstrates that the only afferent nerve that elicits the GCR in pigs is the iSLN, and that it should remain the focus of research for the rehabilitation of patients with absent or defective reflex vocal fold adduction.

AB - Objectives: The aim of this study was to identify a panel of sensory nerves capable of eliciting an evoked glottic closure reflex (GCR) and to quantify the glottic closing force (GCF) of these responses in a porcine model. Methods: In 5 pigs, the internal branch of the superior laryngeal nerve (iSLN) and the trigeminal, pharyngeal plexus, glossopharyngeal, radial, and intercostal nerves were surgically isolated and electrically stimulated. During stimulation of each nerve, the GCR was detected by laryngeal electromyography and the GCF was measured with a pressure transducer. Results: The only nerve that elicited the GCR in the 5 pigs was the iSLN. The average GCF was 288.9 mm Hg. Conclusions: This study demonstrates that the only afferent nerve that elicits the GCR in pigs is the iSLN, and that it should remain the focus of research for the rehabilitation of patients with absent or defective reflex vocal fold adduction.

KW - Afferent nerve

KW - Electrical stimulation

KW - Glottis

KW - Neuron

KW - Reflex

UR - http://www.scopus.com/inward/record.url?scp=54249095507&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=54249095507&partnerID=8YFLogxK

U2 - 10.1177/000348940811701008

DO - 10.1177/000348940811701008

M3 - Article

VL - 117

SP - 749

EP - 752

JO - Annals of Otology, Rhinology and Laryngology

JF - Annals of Otology, Rhinology and Laryngology

SN - 0003-4894

IS - 10

ER -