Regenerative medicine for neurological disorders

Dong Hyuk Park, David J. Eve, Yong Gu Chung, Paul R. Sanberg

    Research output: Contribution to journalReview articlepeer-review

    28 Citations (Scopus)

    Abstract

    The annual meeting of the American Society for Neural Therapy and Repair (ASNTR) has always introduced us to top-notch and up-to-date approaches for regenerative medicine related to neuroscience, ranging from stem cell-based therapy to novel drugs. The 16th ASNTR meeting focused on a variety of different topics, including the unknown pathogenesis or mechanisms of specific neurodegenerative diseases, stem cell biology, and development of novel alternative medicines or devices. Newly developed stem cells, such as amniotic epithelial stem cells and induced pluripotent stem cells, as well as well-known traditional stem cells, such as neural, embryonic, bone marrow mesenchymal, and human umbilical cord blood-derived stem cells, were reported. A number of commercialized stem cells were also covered at this meeting. Fetal neural tissues, such as ventral mesencephalon, striatum, and Schwann cells, were investigated for neurodegenerative diseases or spinal cord injury. A number of studies focused on novel methods for drug monitoring or graft tracking, and combination therapy with stem cells and medicine, such as cytokines or trophic factors. Finally, the National Institutes of Health guidelines for human stem cell research, clinical trials of commercialized stem cells without larger animal testing, and prohibition of medical tourism were big controversial issues that led to heated discussion.

    Original languageEnglish
    Pages (from-to)470-489
    Number of pages20
    JournalTheScientificWorldJournal
    Volume10
    DOIs
    Publication statusPublished - 2010 Mar 16

    Keywords

    • ASNTR
    • Alternative medicine
    • Neuroscience
    • Regenerative medicine
    • Stem cell
    • Transplantation

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Environmental Science(all)

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