Registration-free infant cortical surface parcellation using deep convolutional neural networks

Zhengwang Wu, Gang Li, Li Wang, Feng Shi, Weili Lin, John H. Gilmore, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Automatic parcellation of infant cortical surfaces into anatomical regions of interest (ROIs) is of great importance in brain structural and functional analysis. Conventional cortical surface parcellation methods suffer from two main issues: (1) Cortical surface registration is needed for establishing the atlas-to-individual correspondences; (2) The mapping from cortical shape to the parcellation labels requires designing of specific hand-crafted features. To address these issues, in this paper, we propose a novel cortical surface parcellation method, which is free of surface registration and designing of hand-crafted features, based on deep convolutional neural network (DCNN). Our main idea is to formulate surface parcellation as a patch-wise classification problem. Briefly, we use DCNN to train a classifier, whose inputs are the local cortical surface patches with multi-channel cortical shape descriptors such as mean curvature, sulcal depth, and average convexity; while the outputs are the parcellation label probabilities of cortical vertices. To enable effective convolutional operation on the surface data, we project each spherical surface patch onto its intrinsic tangent plane by a geodesic-distance-preserving mapping. Then, after classification, we further adopt the graph cuts method to improve spatial consistency of the parcellation. We have validated our method based on 90 neonatal cortical surfaces with manual parcellations, showing superior accuracy and efficiency of our proposed method.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings
EditorsAlejandro F. Frangi, Christos Davatzikos, Gabor Fichtinger, Carlos Alberola-López, Julia A. Schnabel
PublisherSpringer Verlag
Pages672-680
Number of pages9
ISBN (Print)9783030009304
DOIs
Publication statusPublished - 2018 Jan 1
Externally publishedYes
Event21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018 - Granada, Spain
Duration: 2018 Sep 162018 Sep 20

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11072 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018
CountrySpain
CityGranada
Period18/9/1618/9/20

Fingerprint

Registration
Neural Networks
Neural networks
Patch
Labels
Tangent plane
Shape Descriptor
Geodesic Distance
Functional analysis
Graph Cuts
Atlas
Functional Analysis
Structural Analysis
Region of Interest
Mean Curvature
Structural analysis
Classification Problems
Convexity
Brain
Classifiers

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this

Wu, Z., Li, G., Wang, L., Shi, F., Lin, W., Gilmore, J. H., & Shen, D. (2018). Registration-free infant cortical surface parcellation using deep convolutional neural networks. In A. F. Frangi, C. Davatzikos, G. Fichtinger, C. Alberola-López, & J. A. Schnabel (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings (pp. 672-680). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-030-00931-1_77

Registration-free infant cortical surface parcellation using deep convolutional neural networks. / Wu, Zhengwang; Li, Gang; Wang, Li; Shi, Feng; Lin, Weili; Gilmore, John H.; Shen, Dinggang.

Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. ed. / Alejandro F. Frangi; Christos Davatzikos; Gabor Fichtinger; Carlos Alberola-López; Julia A. Schnabel. Springer Verlag, 2018. p. 672-680 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 11072 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wu, Z, Li, G, Wang, L, Shi, F, Lin, W, Gilmore, JH & Shen, D 2018, Registration-free infant cortical surface parcellation using deep convolutional neural networks. in AF Frangi, C Davatzikos, G Fichtinger, C Alberola-López & JA Schnabel (eds), Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 11072 LNCS, Springer Verlag, pp. 672-680, 21st International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2018, Granada, Spain, 18/9/16. https://doi.org/10.1007/978-3-030-00931-1_77
Wu Z, Li G, Wang L, Shi F, Lin W, Gilmore JH et al. Registration-free infant cortical surface parcellation using deep convolutional neural networks. In Frangi AF, Davatzikos C, Fichtinger G, Alberola-López C, Schnabel JA, editors, Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. Springer Verlag. 2018. p. 672-680. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). https://doi.org/10.1007/978-3-030-00931-1_77
Wu, Zhengwang ; Li, Gang ; Wang, Li ; Shi, Feng ; Lin, Weili ; Gilmore, John H. ; Shen, Dinggang. / Registration-free infant cortical surface parcellation using deep convolutional neural networks. Medical Image Computing and Computer Assisted Intervention – MICCAI 2018 - 21st International Conference, 2018, Proceedings. editor / Alejandro F. Frangi ; Christos Davatzikos ; Gabor Fichtinger ; Carlos Alberola-López ; Julia A. Schnabel. Springer Verlag, 2018. pp. 672-680 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
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