Registration of longitudinal image sequences with implicit template and spatial-temporal heuristics

Guorong Wu, Qian Wang, Hongjun Jia, Dinggang Shen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Citations (Scopus)

Abstract

Accurate measurement of longitudinal changes of anatomical structure is important and challenging in many clinical studies. Also, for identification of disease-affected regions due to the brain disease, it is extremely necessary to register a population data to the common space simultaneously. In this paper, we propose a new method for simultaneous longitudinal and groupwise registration of a set of longitudinal data acquired from multiple subjects. Our goal is to 1) consistently measure the longitudinal changes from a sequence of longitudinal data acquired from the same subject; and 2) jointly align all image data (acquired from all time points of all subjects) to a hidden common space. To achieve these two goals, we first introduce a set of temporal fiber bundles to explore the spatial-temporal behavior of anatomical changes in each longitudinal data of the same subject. Then, a probabilistic model is built upon the hidden state of spatial smoothness and temporal continuity on the fibers. Finally, the transformation fields that connect each time-point image of each subject to the common space are simultaneously estimated by the expectation maximization (EM) approach, via the maximum a posterior (MAP) estimation of probabilistic models. Promising results are obtained to quantitatively measure the longitudinal changes of hippocampus volume, indicating better performance of our method than the conventional pairwise methods.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings
Pages618-625
Number of pages8
EditionPART 2
DOIs
Publication statusPublished - 2010
Event13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010 - Beijing, China
Duration: 2010 Sep 202010 Sep 24

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume6362 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other13th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2010
CountryChina
CityBeijing
Period10/9/2010/9/24

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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    Wu, G., Wang, Q., Jia, H., & Shen, D. (2010). Registration of longitudinal image sequences with implicit template and spatial-temporal heuristics. In Medical Image Computing and Computer-Assisted Intervention, MICCAI2010 - 13th International Conference, Proceedings (PART 2 ed., pp. 618-625). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 6362 LNCS, No. PART 2). https://doi.org/10.1007/978-3-642-15745-5_76