Relationship between fractal dimension and morphological features of Cephalosporium acremonium M25 in a 30-1 bioreactor culture

Jung Soo Lim, Jung Mo Kim, Jong Chae Kim, Chang Ho Kim, Dae Ryook Yang, Hyo-Ihl Chang, Seung Wook Kim

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In a 30-1 bioreactor culture, whole differentiation occurred from 48 h, and then proceeded rapidly. As swollen hyphal fragments and arthrospores increased, cephalosporin C (CPC) production increased exponentially to 1.85 g/l-1 at 72 h. To explain the morphological changes of Cephalosporium acremonium M25 more quantitatively, specific differentiation rates and fractal analysis were employed. Specific differentiation rates of morphological factors varied greatly during the period of culture time from 48 h to 72 h, when CPC production increased significantly. Changes of fractal dimensions showed a pattern similar to that of the specific rate of arthrospores. Furthermore, it was inversely related to the specific rate of tips. Overall, it was suggested that the fractal dimension had potential for a new morphological parameter of fungal morphology, showing complex differentiation patterns.

Original languageEnglish
Pages (from-to)971-976
Number of pages6
JournalJournal of Microbiology and Biotechnology
Volume15
Issue number5
Publication statusPublished - 2005 Oct 1

Fingerprint

Acremonium
Fractals
Bioreactors
Fractal dimension
cephalosporin C

Keywords

  • Cephalosporin C
  • Cephalosporium acremonium M25
  • Fractal dimension
  • Morphology
  • Specific differentiation rate

ASJC Scopus subject areas

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Microbiology
  • Bioengineering

Cite this

Relationship between fractal dimension and morphological features of Cephalosporium acremonium M25 in a 30-1 bioreactor culture. / Lim, Jung Soo; Kim, Jung Mo; Kim, Jong Chae; Kim, Chang Ho; Yang, Dae Ryook; Chang, Hyo-Ihl; Kim, Seung Wook.

In: Journal of Microbiology and Biotechnology, Vol. 15, No. 5, 01.10.2005, p. 971-976.

Research output: Contribution to journalArticle

@article{8fe9bc4c909c4fa7bbe77235f9357b85,
title = "Relationship between fractal dimension and morphological features of Cephalosporium acremonium M25 in a 30-1 bioreactor culture",
abstract = "In a 30-1 bioreactor culture, whole differentiation occurred from 48 h, and then proceeded rapidly. As swollen hyphal fragments and arthrospores increased, cephalosporin C (CPC) production increased exponentially to 1.85 g/l-1 at 72 h. To explain the morphological changes of Cephalosporium acremonium M25 more quantitatively, specific differentiation rates and fractal analysis were employed. Specific differentiation rates of morphological factors varied greatly during the period of culture time from 48 h to 72 h, when CPC production increased significantly. Changes of fractal dimensions showed a pattern similar to that of the specific rate of arthrospores. Furthermore, it was inversely related to the specific rate of tips. Overall, it was suggested that the fractal dimension had potential for a new morphological parameter of fungal morphology, showing complex differentiation patterns.",
keywords = "Cephalosporin C, Cephalosporium acremonium M25, Fractal dimension, Morphology, Specific differentiation rate",
author = "Lim, {Jung Soo} and Kim, {Jung Mo} and Kim, {Jong Chae} and Kim, {Chang Ho} and Yang, {Dae Ryook} and Hyo-Ihl Chang and Kim, {Seung Wook}",
year = "2005",
month = "10",
day = "1",
language = "English",
volume = "15",
pages = "971--976",
journal = "Journal of Microbiology and Biotechnology",
issn = "1017-7825",
publisher = "Korean Society for Microbiolog and Biotechnology",
number = "5",

}

TY - JOUR

T1 - Relationship between fractal dimension and morphological features of Cephalosporium acremonium M25 in a 30-1 bioreactor culture

AU - Lim, Jung Soo

AU - Kim, Jung Mo

AU - Kim, Jong Chae

AU - Kim, Chang Ho

AU - Yang, Dae Ryook

AU - Chang, Hyo-Ihl

AU - Kim, Seung Wook

PY - 2005/10/1

Y1 - 2005/10/1

N2 - In a 30-1 bioreactor culture, whole differentiation occurred from 48 h, and then proceeded rapidly. As swollen hyphal fragments and arthrospores increased, cephalosporin C (CPC) production increased exponentially to 1.85 g/l-1 at 72 h. To explain the morphological changes of Cephalosporium acremonium M25 more quantitatively, specific differentiation rates and fractal analysis were employed. Specific differentiation rates of morphological factors varied greatly during the period of culture time from 48 h to 72 h, when CPC production increased significantly. Changes of fractal dimensions showed a pattern similar to that of the specific rate of arthrospores. Furthermore, it was inversely related to the specific rate of tips. Overall, it was suggested that the fractal dimension had potential for a new morphological parameter of fungal morphology, showing complex differentiation patterns.

AB - In a 30-1 bioreactor culture, whole differentiation occurred from 48 h, and then proceeded rapidly. As swollen hyphal fragments and arthrospores increased, cephalosporin C (CPC) production increased exponentially to 1.85 g/l-1 at 72 h. To explain the morphological changes of Cephalosporium acremonium M25 more quantitatively, specific differentiation rates and fractal analysis were employed. Specific differentiation rates of morphological factors varied greatly during the period of culture time from 48 h to 72 h, when CPC production increased significantly. Changes of fractal dimensions showed a pattern similar to that of the specific rate of arthrospores. Furthermore, it was inversely related to the specific rate of tips. Overall, it was suggested that the fractal dimension had potential for a new morphological parameter of fungal morphology, showing complex differentiation patterns.

KW - Cephalosporin C

KW - Cephalosporium acremonium M25

KW - Fractal dimension

KW - Morphology

KW - Specific differentiation rate

UR - http://www.scopus.com/inward/record.url?scp=27944452681&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27944452681&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:27944452681

VL - 15

SP - 971

EP - 976

JO - Journal of Microbiology and Biotechnology

JF - Journal of Microbiology and Biotechnology

SN - 1017-7825

IS - 5

ER -