Relationship between left atrial appendage emptying and left atrial function using cardiac magnetic resonance in patients with atrial fibrillation: comparison with transesophageal echocardiography

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Abstract

To compare cardiac magnetic resonance (CMR) quantifications of left atrium (LA) function and left atrial appendage (LAA) emptying depending on the presence of LA spontaneous echogenic contrast (LA-SEC) on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). A total of 48 patients with AF underwent sequential CMR examination and TEE in preparation for catheter ablation. The CMR protocol included cine and velocity encoding (VENC) sequences for evaluation of both LA function and LAA emptying. The peak blood velocity of LAA just before left ventricle systole was defined as the LAA emptying velocity (LAA-EV). Depending on the presence of LA-SEC on TEE, patients were divided into two groups, the SEC group (n = 15) and the non-SEC group (n = 33). Mean LAA-EV was significantly greater in the non-SEC group than in the SEC group (54.5 ± 24.8 ml/s vs. 26.0 ± 22.6 ml/s, P < 0.01). LAA-EV had a significant positive relationship (P < 0.05) with LAA backflow velocity, as assessed using TEE. Use of an optimal LAA-EV cutoff value of 35 ml/s to predict LA-SEC yielded a sensitivity of 80.0 %, a specificity of 75.7 %, and positive and negative predictive values of 58.8 and 83.9 %, respectively. Using VENC-CMR, LAA-EV is associated with LA function and can be useful for predicting LA-SEC in patients with AF.

Original languageEnglish
Pages (from-to)163-171
Number of pages9
JournalInternational Journal of Cardiovascular Imaging
Volume32
DOIs
Publication statusPublished - 2016 Jun 1

Fingerprint

Left Atrial Function
Atrial Appendage
Transesophageal Echocardiography
Atrial Fibrillation
Magnetic Resonance Spectroscopy
Heart Atria
Catheter Ablation
Systole
Heart Ventricles

Keywords

  • Atrial fibrillation
  • Echocardiography
  • Left atrial appendage
  • Left atrium
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

@article{1202474ab1d64da796726b570eabbfb0,
title = "Relationship between left atrial appendage emptying and left atrial function using cardiac magnetic resonance in patients with atrial fibrillation: comparison with transesophageal echocardiography",
abstract = "To compare cardiac magnetic resonance (CMR) quantifications of left atrium (LA) function and left atrial appendage (LAA) emptying depending on the presence of LA spontaneous echogenic contrast (LA-SEC) on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). A total of 48 patients with AF underwent sequential CMR examination and TEE in preparation for catheter ablation. The CMR protocol included cine and velocity encoding (VENC) sequences for evaluation of both LA function and LAA emptying. The peak blood velocity of LAA just before left ventricle systole was defined as the LAA emptying velocity (LAA-EV). Depending on the presence of LA-SEC on TEE, patients were divided into two groups, the SEC group (n = 15) and the non-SEC group (n = 33). Mean LAA-EV was significantly greater in the non-SEC group than in the SEC group (54.5 ± 24.8 ml/s vs. 26.0 ± 22.6 ml/s, P < 0.01). LAA-EV had a significant positive relationship (P < 0.05) with LAA backflow velocity, as assessed using TEE. Use of an optimal LAA-EV cutoff value of 35 ml/s to predict LA-SEC yielded a sensitivity of 80.0 {\%}, a specificity of 75.7 {\%}, and positive and negative predictive values of 58.8 and 83.9 {\%}, respectively. Using VENC-CMR, LAA-EV is associated with LA function and can be useful for predicting LA-SEC in patients with AF.",
keywords = "Atrial fibrillation, Echocardiography, Left atrial appendage, Left atrium, Magnetic resonance imaging",
author = "Hwang, {Sung Ho} and Oh, {Yu Whan} and Kim, {Mi Na} and Seong-Mi Park and Shim, {Wan Joo} and Jaemin Shim and Jongil Choi and Kim, {Young Hoon}",
year = "2016",
month = "6",
day = "1",
doi = "10.1007/s10554-016-0893-1",
language = "English",
volume = "32",
pages = "163--171",
journal = "International Journal of Cardiovascular Imaging",
issn = "1569-5794",
publisher = "Springer Netherlands",

}

TY - JOUR

T1 - Relationship between left atrial appendage emptying and left atrial function using cardiac magnetic resonance in patients with atrial fibrillation

T2 - comparison with transesophageal echocardiography

AU - Hwang, Sung Ho

AU - Oh, Yu Whan

AU - Kim, Mi Na

AU - Park, Seong-Mi

AU - Shim, Wan Joo

AU - Shim, Jaemin

AU - Choi, Jongil

AU - Kim, Young Hoon

PY - 2016/6/1

Y1 - 2016/6/1

N2 - To compare cardiac magnetic resonance (CMR) quantifications of left atrium (LA) function and left atrial appendage (LAA) emptying depending on the presence of LA spontaneous echogenic contrast (LA-SEC) on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). A total of 48 patients with AF underwent sequential CMR examination and TEE in preparation for catheter ablation. The CMR protocol included cine and velocity encoding (VENC) sequences for evaluation of both LA function and LAA emptying. The peak blood velocity of LAA just before left ventricle systole was defined as the LAA emptying velocity (LAA-EV). Depending on the presence of LA-SEC on TEE, patients were divided into two groups, the SEC group (n = 15) and the non-SEC group (n = 33). Mean LAA-EV was significantly greater in the non-SEC group than in the SEC group (54.5 ± 24.8 ml/s vs. 26.0 ± 22.6 ml/s, P < 0.01). LAA-EV had a significant positive relationship (P < 0.05) with LAA backflow velocity, as assessed using TEE. Use of an optimal LAA-EV cutoff value of 35 ml/s to predict LA-SEC yielded a sensitivity of 80.0 %, a specificity of 75.7 %, and positive and negative predictive values of 58.8 and 83.9 %, respectively. Using VENC-CMR, LAA-EV is associated with LA function and can be useful for predicting LA-SEC in patients with AF.

AB - To compare cardiac magnetic resonance (CMR) quantifications of left atrium (LA) function and left atrial appendage (LAA) emptying depending on the presence of LA spontaneous echogenic contrast (LA-SEC) on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). A total of 48 patients with AF underwent sequential CMR examination and TEE in preparation for catheter ablation. The CMR protocol included cine and velocity encoding (VENC) sequences for evaluation of both LA function and LAA emptying. The peak blood velocity of LAA just before left ventricle systole was defined as the LAA emptying velocity (LAA-EV). Depending on the presence of LA-SEC on TEE, patients were divided into two groups, the SEC group (n = 15) and the non-SEC group (n = 33). Mean LAA-EV was significantly greater in the non-SEC group than in the SEC group (54.5 ± 24.8 ml/s vs. 26.0 ± 22.6 ml/s, P < 0.01). LAA-EV had a significant positive relationship (P < 0.05) with LAA backflow velocity, as assessed using TEE. Use of an optimal LAA-EV cutoff value of 35 ml/s to predict LA-SEC yielded a sensitivity of 80.0 %, a specificity of 75.7 %, and positive and negative predictive values of 58.8 and 83.9 %, respectively. Using VENC-CMR, LAA-EV is associated with LA function and can be useful for predicting LA-SEC in patients with AF.

KW - Atrial fibrillation

KW - Echocardiography

KW - Left atrial appendage

KW - Left atrium

KW - Magnetic resonance imaging

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U2 - 10.1007/s10554-016-0893-1

DO - 10.1007/s10554-016-0893-1

M3 - Article

C2 - 27119163

AN - SCOPUS:84977074297

VL - 32

SP - 163

EP - 171

JO - International Journal of Cardiovascular Imaging

JF - International Journal of Cardiovascular Imaging

SN - 1569-5794

ER -