Relationship between plasma adiponectin levels and the metabolic syndrome among Korean people

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We investigated the relationship between plasma adiponectin levels and the parameters of the metabolic syndrome among Koreans. In 67 male and 115 female subjects, aged from 30 to 70 years, plasma adiponectin levels were positively correlated with HDL-cholesterol levels (r = 0.295, P<0.001), but negatively correlated with waist circumference (r = -0.140, P = 0.020), triglycerides (r = -0.174, P = 0.021), fasting plasma glucose (r = -0.159, P = 0.036), fasting plasma insulin (r = -0.172, P = 0.023) and HOMA-IR (r = -0.182, P<0.001), after adjustment for age, sex, and BMI. Stepwise multiple regression analyses revealed that HDL-cholesterol, sex, and HOMA-IR were the independent associated factors for plasma adiponectin levels. Multiple logistic analyses demonstrated that HOMA-IR, BMI, and age were the predominant independent factors associated with the metabolic syndrome, while plasma adiponectin levels exhibited a protective effect against the presence of the metabolic syndrome according to both NCEP ATP III criteria and IDF definition. Hypoadiponectinemia is associated with the phenotype of the metabolic syndrome as well as components of the metabolic syndrome.

Original languageEnglish
Pages (from-to)247-254
Number of pages8
JournalEndocrine Journal
Volume53
Issue number2
DOIs
Publication statusPublished - 2006 Apr 26

Keywords

  • Adiponectin
  • Korean
  • Metabolic syndrome

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Fingerprint Dive into the research topics of 'Relationship between plasma adiponectin levels and the metabolic syndrome among Korean people'. Together they form a unique fingerprint.

  • Cite this