Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study

Tae Hyub Lee, Gwan Gyu Song, Sung Jae Choi, Hongdeok Seok, Jae Hyun Jung

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

BACKGROUND: Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Korea. METHODS: We conducted a nationwide cross-sectional study by using the Korea National Health and Nutrition Examination Survey, which collected data for four years between 2008 and 2012. A total of 25,828 eligible participants were included. To balance the distribution of baseline characteristics, we used propensity score-matching. A multivariable logistic regression model was employed and we calculated the odds ratios (ORs) and 95% confidence intervals (CI) for the odds of the participants with RA on CAD prevalence. RESULTS: The prevalence of RA in Korea from 2008 to 2012 was 0.6% and RA was predominant among elderly women. The prevalence of CAD in patients with RA was significantly higher than in general population. After propensity score-matching to balance the confounding factors, RA was significantly associated with CAD (OR 2.97, 95% CI 1.15-7.68, P = 0.02). CONCLUSIONS: The prevalence of RA in South Korea was comparable to the worldwide data, and the presence of CAD in RA patients was more than two-fold.

Original languageEnglish
Pages (from-to)40
Number of pages1
JournalAdvances in rheumatology (London, England)
Volume59
Issue number1
DOIs
Publication statusPublished - 2019 Aug 27

Keywords

  • Angina pectoris
  • Myocardial infarction
  • Prevalence
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Rheumatology

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