Reliability and validity of the Korean version of the European organization for research and treatment of cancer quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy

Hye Young Kim, Jeong Hee Kang, Hyun Jo Youn, Hyang Sook So, Chi Eun Song, Seo Young Chae, Sung Hoo Jung, Sung Reul Kim, Ji Young Kim

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Purpose: This study was performed to assess the reliability and validity of the Korean version of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Chemotherapy-induced peripheral neuropathy 20 items (EORTC QLQ-CIPN20) in patients receiving neurotoxic chemotherapy. Methods: A convenience sample of 249 Korean cancer patients, previously or currently, being treated with peripheral neurotoxic chemotherapeutic agents were asked to fill in the questionnaire. Collected data were analyzed using SPSS 21.0 and AMOS 21.0. Construct validity, known-group validity, concurrent validity, and internal consistency reliability of the Korean version of the QLQ-CIPN20 were evaluated. Results: Factor analysis confirmed 3 dimensions of CIPN: sensory, motor, and autonomic. The factor loadings of the 20 items on the 3 subscales ranged from. 38 to. 85. The 3 subscale-model was validated by confirmatory factor analysis (GFI=.90, AGFI=.86, RMSR=.05, NFI=.87, and CFI=.94), and concurrent validity was demonstrated with the EORTC QLQC30. Furthermore, the QLQ-CIPN20 established known-group validity. The Cronbach’s alpha coefficients for internal consistency of the subscales ranged from. 73 to. 89. Conclusion: The Korean version of the EORTC QLQ-CIPN20 showed satisfactory construct, concurrent, and known-group validity, as well as internal reliability.

Original languageEnglish
Pages (from-to)735-742
Number of pages8
JournalJournal of Korean Academy of Nursing
Issue number6
Publication statusPublished - 2014 Dec 1
Externally publishedYes



  • Chemotherapy
  • Peripheral neuropathies
  • Reliability
  • Validity

ASJC Scopus subject areas

  • Nursing(all)

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