Reproducibility of regional pulse wave velocity in healthy subjects

Nak Bum Lee, Chang Gyu Park

    Research output: Contribution to journalArticlepeer-review

    7 Citations (Scopus)

    Abstract

    Background/Aims: Despite the clinical importance and widespread use of pulse wave velocity (PWV), there are no standards for pulse sensors or for system requirements to ensure accurate pulse wave measurement. We assessed the reproducibility of PWV values using a newly developed PWV measurement system. Methods: The system used in this study was the PP-1000, which simultaneously provides regional PWV values from arteries at four different sites (carotid, femoral, radial, and dorsalis pedis). Seventeen healthy male subjects without any cardiovascular disease participated in this study. Two observers performed two consecutive measurements in the same subject in random order. To evaluate the reproducibility of the system, two sets of analyses (within-observer and between-observer) were performed. Results: The means±SD of PWV for the aorta, arm, and leg were 7.0±1.48, 8.43±1.14, and 8.09±0.98 m/s as measured by observer A and 6.76±1.00, 7.97±0.80, and 7.97±0.72 m/s by observer B, respectively. Betweenobserver differences for the aorta, arm, and leg were 0.14±0.62, 0.18±0.84, and 0.07±0.86 m/s, respectively, and the correlation coefficients were high, especially for aortic PWV (r=0.93). All the measurements showed significant correlation coefficients, ranging from 0.94 to 0.99. Conclusions: The PWV measurement system used in this study provides accurate analysis results with high reproducibility. It is necessary to provide an accurate algorithm for the detection of additional features such as flow wave, reflection wave, and dicrotic notch from a pulse waveform.

    Original languageEnglish
    Pages (from-to)19-23
    Number of pages5
    JournalKorean Journal of Internal Medicine
    Volume24
    Issue number1
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Arterial stiffness
    • Cardiovascular disease
    • Pulse sensor
    • Pulse wave velocity
    • Reproducibility

    ASJC Scopus subject areas

    • Internal Medicine

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