Research Update: Nanoscale surface potential analysis of MoS2 field-effect transistors for biomolecular detection using Kelvin probe force microscopy

Min Hyung Kim, Heekyeong Park, Hyungbeen Lee, Kihwan Nam, Seokhwan Jeong, Inturu Omkaram, Dae Sung Yoon, Sei Young Lee, Sunkook Kim, Sang Woo Lee

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We used high-resolution Kelvin probe force microscopy (KPFM) to investigate the immobilization of a prostate specific antigen (PSA) antibody by measuring the surface potential (SP) on a MoS2 surface over an extensive concentration range (1 pg/ml-100 μg/ml). After PSA antibody immobilization, we demonstrated that the SP on the MoS2 surface characterized by KPFM strongly correlated to the electrical signal of a MoS2 bioFET. This demonstration can not only be used to optimize the immobilization conditions for captured molecules, but can also be applied as a diagnostic tool to complement the electrical detection of a MoS2 FET biosensor.

Original languageEnglish
Article number100701
JournalAPL Materials
Issue number10
Publication statusPublished - 2016 Oct 1


ASJC Scopus subject areas

  • Materials Science(all)
  • Engineering(all)

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