Resistin Concentration is Increased in the Peritoneal Fluid of Women with Endometriosis

Kyong Wook Yi, Jung Ho Shin, Hyun Tae Park, Tak Kim, Sun Haeng Kim, Jun Young Hur

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    15 Citations (Scopus)

    Abstract

    Citation Yi KW, Shin J-H, Park HT, Kim T, Kim SH, Hur J-Y. Resistin concentration is increased in the peritoneal fluid of women with endometriosis. Am J Reprod Immunol 2010 Problem The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis. Method of study PF sampling was obtained from women with (n=48) and without endometriosis (n=36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay. Results The mean concentration of PF resistin was significantly higher in women with endometriosis compared to the controls. PF resistin concentrations were not associated with any of the anthropometric indices. The PF adiponectin did not differ between the two groups, but showed a significant association with the weight, body mass index, and hip circumference. After adjusting for these factors, PF adiponectin expression was not associated with endometriosis. Conclusion The findings of this study suggest a potent role for resistin in endometriosis. Further studies are needed to elucidate the biological implications of resistin in endometriosis.

    Original languageEnglish
    Pages (from-to)318-323
    Number of pages6
    JournalAmerican Journal of Reproductive Immunology
    Volume64
    Issue number5
    DOIs
    Publication statusPublished - 2010 Nov

    Keywords

    • Endometriosis
    • Peritoneal fluid
    • Resistin

    ASJC Scopus subject areas

    • Immunology and Allergy
    • Immunology
    • Reproductive Medicine
    • Obstetrics and Gynaecology

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