Response to chloroquine of Plasmodium vivax among South Korean soldiers

Chae Seung Lim, Yong Ku Kim, K. N. Lee, M. J. Kim, K. H. Kim, D. S. Kim, D. Strickman

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The response to standard chloroquine treatment was evaluated, by microscopical examination of blood-smears, among 81 soldiers diagnosed with Plasmodium vivax malaria in South Korea in 1996. The smears were prepared pre-treatment and 3, 14 and 28 days after starting chemotherapy. Parasitaemias were determined after staining the smears with Giemsa's stain. Blood samples from the patients who were not smear-negative by day 3 were carefully checked for parasites, by staining smears with Acridine Orange and by a PCR-based assay. Only two of the patients appeared to be parasitaemic on day 14 and were therefore considered treatment failures. Although both were apparently cured after additional therapy with the same regimen, one had a recurrence 8 months later. Most cases of recent, resurgent malaria in South Korea therefore appear to sensitive to chloroquine.

Original languageEnglish
Pages (from-to)565-568
Number of pages4
JournalAnnals of Tropical Medicine and Parasitology
Volume93
Issue number6
DOIs
Publication statusPublished - 1999 Sep 28

Fingerprint

Plasmodium vivax
Military Personnel
Chloroquine
Republic of Korea
Azure Stains
Staining and Labeling
Vivax Malaria
Acridine Orange
Parasitemia
Treatment Failure
Malaria
Parasites
Therapeutics
Recurrence
Drug Therapy
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Immunology

Cite this

Response to chloroquine of Plasmodium vivax among South Korean soldiers. / Lim, Chae Seung; Kim, Yong Ku; Lee, K. N.; Kim, M. J.; Kim, K. H.; Kim, D. S.; Strickman, D.

In: Annals of Tropical Medicine and Parasitology, Vol. 93, No. 6, 28.09.1999, p. 565-568.

Research output: Contribution to journalArticle

Lim, Chae Seung ; Kim, Yong Ku ; Lee, K. N. ; Kim, M. J. ; Kim, K. H. ; Kim, D. S. ; Strickman, D. / Response to chloroquine of Plasmodium vivax among South Korean soldiers. In: Annals of Tropical Medicine and Parasitology. 1999 ; Vol. 93, No. 6. pp. 565-568.
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