Retinal nerve fiber layer configuration in eyes with Epiretinal membrane

Jaeryung Oh, Jong Hyun Oh, Jae Rock Do, Minwook Chang, Choul Yong Park

    Research output: Contribution to journalArticlepeer-review

    4 Citations (Scopus)

    Abstract

    Purpose. To characterize configurations of the optic nerve head (ONH) and peripapillary retinal nerve fiber layer (RNFL) eyes with epiretinal membrane (ERM). Methods. We reviewed medical records of consecutive patientswith ERMwhowere examined between September 2012 and August 2013. Patientswere categorized based on the severity of ERMon fundus imaging; patientswith ERMbutwithout retinal distortionwere in group 1, and patients with ERMand retinal distortionwere in group 2.Optic nerve head and RNFL parameters measured by spectral domain optical coherence tomographywere assessed and compared between eyes with ERMand normal fellow eyes. Results. There were no significant differences in ONH and RNFL parameters between ERM eyes and normal fellow eyes in group 1 (n = 12). In group 2 (n = 33), cup volume was smaller (p = 0.020), temporal quadrant RNFL thickness was greater by 18.8 ± 16.6 μm (p < 0.001), and RNFL peak angle was smaller by 18.7 ± 25.3 degrees in ERM eyes compared with fellow eyes (p = 0.001). In the 15 patients in group 2 who underwent ERM removal, temporal quadrant RNFL thickness decreased and the RNFL peak angle increased after the surgery (p = 0.008 and p = 0.001, respectively). Conclusions. The configurations of the ONH and peripapillary RNFL in eyes with ERM were different from those in fellow eyes. The characteristic configurations of RNFL such as small peak angle and temporal quadrant thickening may be considered when evaluating parameters as measured by spectral domain optical coherence tomography.

    Original languageEnglish
    Pages (from-to)1328-1334
    Number of pages7
    JournalOptometry and Vision Science
    Volume91
    Issue number11
    DOIs
    Publication statusPublished - 2014 Nov 1

    Keywords

    • epiretinalmembrane
    • glaucoma
    • optic nerve head
    • peripapillary retinal nerve fiber layer
    • spectral domain optical coherence tomography

    ASJC Scopus subject areas

    • Ophthalmology
    • Optometry

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